Post‐functionalization of Organoboranes by Cu‐Catalyzed Azide Alkyne [3+2]‐Cycloaddition Reaction
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202400580
Abstract: The copper‐catalyzed azide alkyne [3+2]‐cycloaddition (CuAAC) reaction of organoboranes represents an attractive area of research within the field of click chemistry, with diverse applications in organic synthesis, medicinal chemistry, or materials science. Despite the potential… read more here.
Keywords: reaction; chemistry; alkyne cycloaddition; catalyzed azide ... See more keywords
Copper-catalyzed azide–alkyne cycloaddition (CuAAC) under mild condition in water: Synthesis, catalytic application and biological activities
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2017.09.024
Abstract: Abstract A series of Cu-N-heterocyclic carbene (Cu-NHC) complexes, 3a-c , were synthesized and characterized by spectroscopic methods such as NMR, HRMS and elemental analysis. The performance of these (Cu-NHC) complexes, 3a-c showed excellent activity in… read more here.
Keywords: cycloaddition; alkyne cycloaddition; azide alkyne; catalyzed azide ... See more keywords
Copper-Catalyzed Azide–Alkyne Cycloaddition (CuAAC) by Functionalized NHC-Based Polynuclear Catalysts: Scope and Mechanistic Insights
Sign Up to like & getrecommendations! Published in 2022 at "Organometallics"
DOI: 10.1021/acs.organomet.2c00246
Abstract: Copper(I) [Cu2(μ-Br)2(tBuImCH2pyCH2L)]n (L = OMe, NEt2, NHtBu) compounds supported by flexible functionalized NHC-based polydentate ligands have been prepared in a one-pot procedure by reacting the corresponding imidazolium salt with an excess of copper powder and… read more here.
Keywords: copper; reaction; catalyzed azide; nhc based ... See more keywords
Rhodium-Catalyzed Azide-Alkyne Cycloaddition of Internal Ynamides: Regioselective Assembly of 5-Amino-triazoles under Mild Conditions
Sign Up to like & getrecommendations! Published in 2017 at "ACS Catalysis"
DOI: 10.1021/acscatal.7b02558
Abstract: A rhodium-catalyzed azide–alkyne cycloaddition of internal ynamides is described. The reaction could be performed in a wide range of solvents, including aqueous media, under mild conditions without careful exclusion of air and moisture, giving a… read more here.
Keywords: cycloaddition; cycloaddition internal; rhodium catalyzed; alkyne cycloaddition ... See more keywords
Enantioselective Rh-Catalyzed Azide-Internal-Alkyne Cycloaddition for the Construction of Axially Chiral 1,2,3-Triazoles.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c01985
Abstract: Significant advances have been achieved for the construction of chiral skeletons containing 1,2,3-triazoles via transition-metal-catalyzed asymmetric azide-alkyne cycloaddition; however, most of them have been limited to terminal alkynes in the synthesis of central chirality via… read more here.
Keywords: azide internal; alkyne cycloaddition; catalyzed azide; axially chiral ... See more keywords
Copper Ligand and Anion Effects: Controlling the Kinetics of the Photoinitiated Copper(I) Catalyzed Azide-Alkyne Cycloaddition Polymerization.
Sign Up to like & getrecommendations! Published in 2018 at "Polymer chemistry"
DOI: 10.1039/c8py01004h
Abstract: The kinetics of photoinduced copper(I) catalyzed azide-alkyne cycloaddition (CuAAC) polymerizations were assessed as a function of copper(II) amine-based ligands. Copper(II) bromide ligated with 1,1,4,7,10,10-hexamethylenetetramine (HMTETA) exhibited the fastest kinetics in both Norrish type(I) and type(II)… read more here.
Keywords: alkyne cycloaddition; copper; azide alkyne; catalyzed azide ... See more keywords
An efficient and easily-accessible ligand for Cu(I)-catalyzed azide-alkyne cycloaddition bioconjugation.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc06348g
Abstract: A novel ligand (6) for copper-catalyzed azide-alkyne cycloaddition (CuAAC) in bioconjugation has been developed. Both in vitro and in vivo experiments indicate that 6 is more efficient and less cytotoxic than the canonical CuAAC ligands.… read more here.
Keywords: easily accessible; alkyne cycloaddition; azide alkyne; catalyzed azide ... See more keywords
Beyond 1,2,3-Triazoles: Formation and Applications of Ketenimines Derived from Copper Catalyzed Azide Alkyne Cycloaddition.
Sign Up to like & getrecommendations! Published in 2022 at "Current organic synthesis"
DOI: 10.2174/1570179420666220929152449
Abstract: The ketenimines represent an interesting class of organic intermediates which has undergone a regrowth as a consequence of recent extensions of copper catalyzed azide alkyne cycloaddition (CuAAC) to other synthetic fields. This review summarizes the… read more here.
Keywords: beyond triazoles; alkyne cycloaddition; catalyzed azide; azide alkyne ... See more keywords
Synthesis of Dense 1,2,3-Triazole Oligomers Consisting Preferentially of 1,5-Disubstituted Units via Ruthenium(II)-Catalyzed Azide–Alkyne Cycloaddition
Sign Up to like & getrecommendations! Published in 2023 at "Polymers"
DOI: 10.3390/polym15092199
Abstract: Ruthenium(II)-catalyzed azide–alkyne cycloaddition (RuAAC) polymerization of t-butyl 4-azido-5-hexynoate (tBuAH), i.e., a heterobifunctional monomer carrying azide and alkyne moieties, was investigated in this study. RuAAC of the monofunctional precursors of tBuAH yielded a dimer possessing a… read more here.
Keywords: ruthenium catalyzed; alkyne cycloaddition; catalyzed azide; ruthenium ... See more keywords