Synthesis of gem-Difluorinated 1,3-Dienes via Synergistic Cu/Pd-Catalyzed Borodifluorovinylation of Alkynes.
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DOI: 10.1021/acs.orglett.2c01875
Abstract: gem-Difluoroalkenes (=CF2), which normally act as metabolically stable bioisosteres for carbonyl groups (C═O), are widely applied in agrochemicals and pharmaceuticals and are also used as building blocks in organic synthesis. Herein, an example of Cu/Pd-catalyzed… read more here.
Keywords: gem difluorinated; gem; catalyzed borodifluorovinylation; difluorinated dienes ... See more keywords