Dinickel catalyzed carbonylation reactions using metal carbonyl reagents as CO sources
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.04.064
Abstract: Abstract Dinickel complexes promote stoichiometric Pauson–Khand reactions of enynes and CO (g). However, catalytic turnover is precluded by the strong binding of CO to the Ni2 active site. This article describes the use of M(CO)x… read more here.
Keywords: carbonylation reactions; reactions using; dinickel catalyzed; catalyzed carbonylation ... See more keywords
Mechanistic Investigation of the Nickel-Catalyzed Carbonylation of Alcohols
Sign Up to like & getrecommendations! Published in 2020 at "Organometallics"
DOI: 10.1021/acs.organomet.0c00082
Abstract: The carbonylation of alcohols represents a straightforward and atom-efficient methodology for the preparation of carboxylic acids. It is desirable to perform these reactions under precious metal-fr... read more here.
Keywords: carbonylation alcohols; investigation nickel; carbonylation; catalyzed carbonylation ... See more keywords
Palladium-Catalyzed Carbonylation of Disulfides and Ethylene: Synthesis of β-Thiopropionate Thioesters.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00422
Abstract: Transforming carbon monoxide (C1) and ethylene (C2) into high value-added chemicals is of great significance from an economic perspective, especially to multifunctionalized C3 compounds. Herein, we developed a palladium-catalyzed thiocarbonylative 1,2-difunctionalization of ethylene. Employing NiXantPhos… read more here.
Keywords: carbonylation disulfides; thiopropionate thioesters; palladium catalyzed; disulfides ethylene ... See more keywords
Nickel-Catalyzed Carbonylation of Cyclopropanol with Benzyl Bromide for Multisubstituted Cyclopentenone Synthesis.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00798
Abstract: Herein, we reported a Ni-catalyzed carbonylation of cyclopropanol with benzyl bromide to afford multisubstituted cyclopentenone under 1 atm of CO. The reaction proceeds through cascade carbonylation of benzyl bromides, followed by generation of nickel homoenolate… read more here.
Keywords: carbonylation; cyclopropanol benzyl; carbonylation cyclopropanol; benzyl ... See more keywords
Charge-Transfer Complex Promoted C-N Bond Activation for Ni-Catalyzed Carbonylation.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b01488
Abstract: A new strategy was developed for activation of C-N bond via formation of an amine-I2 charge-transfer complex, which facilitates the inert C-N bond activation via oxidative addition with Ni(0). This strategy has been successfully applied… read more here.
Keywords: transfer complex; bond; bond activation; activation ... See more keywords
Nickel-Catalyzed Carbonylation of Secondary Trifluoromethylated, Difluoromethylated, and Nonfluorinated Aliphatic Electrophiles with Arylboronic Acids under 1 atm of CO
Sign Up to like & getrecommendations! Published in 2019 at "ACS Catalysis"
DOI: 10.1021/acscatal.9b04038
Abstract: The nickel-catalyzed carbonylation of aliphatic electrophiles with the most straightforward CO remains challenging. Here, we describe an example of the nickel-catalyzed carbonylation of secondary alkyl halides with arylboronic acids under 1 atm of CO. The… read more here.
Keywords: aliphatic electrophiles; carbonylation secondary; arylboronic acids; catalyzed carbonylation ... See more keywords
Synthesis of α-CF3 Amides via Palladium-Catalyzed Carbonylation of 2-Bromo-3,3,3-trifluoropropene
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c08206
Abstract: Amide compounds are important organic compounds, which play an important role in biomedical chemistry, materials science, life science, and other fields. The synthesis of α-CF3 amides, especially compounds containing 3-(trifluoromethyl)-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepine-2-one, has long been a challenge… read more here.
Keywords: cf3; synthesis cf3; palladium catalyzed; cf3 amides ... See more keywords
Realizing Metal-Free Carbene-Catalyzed Carbonylation Reactions with CO.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c09938
Abstract: Many organic and main-group compounds, usually acids or bases, can accelerate chemical reactions when used in substoichiometric quantities, a process known as organocatalysis. In marked contrast, very few of these compounds are able to activate… read more here.
Keywords: carbonylation reactions; carbonylation; carbene; realizing metal ... See more keywords
Light-Mediated Synthesis of Aliphatic Anhydrides by Cu-Catalyzed Carbonylation of Alkyl Halides.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c01224
Abstract: Acid anhydrides are valuable in the chemical industry for their role in synthesizing polymers, pharmaceuticals, and other commodities, but their syntheses often involve multiple steps with precious metal catalysts. The simplest anhydride, acetic anhydride, is… read more here.
Keywords: light mediated; mediated synthesis; catalyzed carbonylation; synthesis aliphatic ... See more keywords
Iodide-Catalyzed Carbonylation–Benzylation of Benzyl Chlorides with Potassium Aryltrifluoroborates under Ambient Pressure of Carbon Monoxide
Sign Up to like & getrecommendations! Published in 2017 at "Synlett"
DOI: 10.1055/s-0036-1591502
Abstract: Tetra- N -butylammonium iodide (TBAI) catalyzed carbonylation–benzylation of unactivated benzyl chlorides with potassium aryltrifluoroborates using CO gas has been developed. This reaction is transition-metal free, is carried out under ambient pressure, and provides a wide… read more here.
Keywords: potassium aryltrifluoroborates; benzyl chlorides; chlorides potassium; carbonylation ... See more keywords