Copper-Catalyzed Carbonylative Cross-Coupling of Arylboronic Acids with N-Chloroamines for the Synthesis of Aryl Amides
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201700352
Abstract: A novel copper-catalyzed carbonylative cross-coupling between N-chloroamines and arylboronics acids has been developed. With copper(I) oxide as the catalyst, various desired amide compounds were produced in moderate to good yields. Functional groups such as iodide… read more here.
Keywords: carbonylative cross; copper; cross coupling; catalyzed carbonylative ... See more keywords
Nickel-Catalyzed Carbonylative Synthesis of Functionalized Alkyl Iodides
Sign Up to like & getrecommendations! Published in 2018 at "iScience"
DOI: 10.1016/j.isci.2018.09.024
Abstract: Summary Functionalized alkyl iodides are important compounds in organic chemistry and biology. In this communication, we developed an interesting nickel-catalyzed carbonylative synthesis of functionalized alkyl iodides from aryl iodides and ethers. With Mo(CO)6 as the… read more here.
Keywords: alkyl iodides; synthesis functionalized; nickel catalyzed; functionalized alkyl ... See more keywords
Pd-catalyzed carbonylative α-arylation of azlactones: A formal four-component coupling route to α,α-disubstituted amino acids
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Catalysis"
DOI: 10.1016/j.jcat.2018.04.027
Abstract: Abstract We report on a Pd-catalyzed carbonylative α-arylation of azlactones derived from alanine, providing facile access to α,α-disubstituted amino acids after an alcoholysis step. A range of aryl iodides proved to be suitable substrates in… read more here.
Keywords: amino acids; disubstituted amino; catalyzed carbonylative; carbonylative arylation ... See more keywords
Iron-catalyzed carbonylative alkyl-acylation of heteroarenes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Catalysis"
DOI: 10.1016/j.jcat.2019.03.001
Abstract: Herein we present an efficient carbonylative protocol for the introduction of an alkyl-acyl group into heteroarenes from cyclobutanone oximes. In the presence of Fe(OTf) 2 catalyst, proceeds via intermolecular alkyl-acylation of different heteroarenes. A broad… read more here.
Keywords: iron catalyzed; catalyzed carbonylative; carbonylative alkyl; alkyl acylation ... See more keywords
Copper-Catalyzed Carbonylative Synthesis of β-Homoprolines from N-Fluoro-sulfonamides.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c00227
Abstract: A new methodology for the carbonylative transformation of N-fluoro-sulfonamides into N-sulfonyl-β-homoproline esters has been described. In the presence of a catalytic amount of Cu(OTf)2, a range of β-homoproline derivatives were prepared in moderate to good… read more here.
Keywords: homoprolines fluoro; synthesis homoprolines; carbonylative synthesis; catalyzed carbonylative ... See more keywords
Rhodium-Catalyzed Carbonylative Synthesis of Aryl Salicylates from Unactivated Phenols.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02133
Abstract: A rhodium-catalyzed carbonylative transformation of unactivated phenols to aryl salicylates is described. This protocol is characterized by utilizing 1,3-rhodium migration as the key step to provide direct access to synthesize o-hydroxyaryl esters. Various desired aryl… read more here.
Keywords: unactivated phenols; rhodium catalyzed; carbonylative synthesis; aryl salicylates ... See more keywords
Palladium-Catalyzed Carbonylative Synthesis of Amide-Containing Indolo[2,1-a]isoquinolines from Alkene-Tethered Indoles and Nitroarenes.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04363
Abstract: In this new procedure, amide-containing indolo[2,1-a]isoquinoline scaffolds were prepared by palladium-catalyzed carbonylative cyclization of alkene-tethered indoles with nitroarenes. By using Mo(CO)6 as the CO source and reductant and nitroarenes as the nitrogen source, this reaction… read more here.
Keywords: containing indolo; catalyzed carbonylative; amide containing; palladium catalyzed ... See more keywords
Palladium Catalyzed Carbonylative Coupling of Alkyl Boron Reagents with Bromodifluoroacetamides
Sign Up to like & getrecommendations! Published in 2018 at "ACS Catalysis"
DOI: 10.1021/acscatal.8b00420
Abstract: A catalytic protocol for the preparation of α,α-difluoro-β-alkyl-β-ketoamides is developed employing a Pd-mediated carbonylative Suzuki coupling between alkylboron reagents and bromodifluoroacetamides with COgen as the CO source. The reaction reveals good functional group tolerance providing… read more here.
Keywords: alkyl; carbonylative coupling; coupling alkyl; palladium catalyzed ... See more keywords
Synthesis of unprotected glyco-alkynones via molybdenum-catalyzed carbonylative Sonogashira cross-coupling reaction
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d1ra08388k
Abstract: Herein we report a novel Mo-catalyzed carbonylative Sonogashira cross-coupling between 2-iodoglycals and terminal alkynes. The reaction displays major improvements compared to a related Pd-catalyzed procedure previously published by our group, such as utilizing unprotected sugar… read more here.
Keywords: cross coupling; catalyzed carbonylative; sonogashira cross; carbonylative sonogashira ... See more keywords
Recyclable palladium-catalyzed carbonylative annulation of 2-iodoanilines with acid anhydrides: A practical synthesis of 2-alkylbenzoxazinones
Sign Up to like & getrecommendations! Published in 2021 at "Synthetic Communications"
DOI: 10.1080/00397911.2021.1966039
Abstract: Abstract A highly efficient heterogeneous palladium-catalyzed carbonylative annulation of 2-iodoanilines and acid anhydrides has been developed. The reaction proceeds effectively in toluene using N,N-diisopropylethylamine (DiPEA) as the base at 100 °C under 2 bar of CO and… read more here.
Keywords: carbonylative annulation; annulation iodoanilines; palladium catalyzed; iodoanilines acid ... See more keywords