Rh(III)-Catalyzed Chemodivergent Annulations between Indoles and Iodonium Carbenes: A Rapid Access to Tricyclic and Tetracyclic N-Heterocylces.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01167
Abstract: Herein, we report an acid-controlled highly tunable selectivity of Rh(III)-catalyzed [4 + 2] and [3 + 3] annulations of N-carboxamide indoles with iodonium ylides lead to form synthetically important tricyclic and tetracyclic N-heterocycles. Here, iodonium… read more here.
Keywords: annulations indoles; catalyzed chemodivergent; iii catalyzed; tricyclic tetracyclic ... See more keywords
Iridium and a Brønsted acid cooperatively catalyzed chemodivergent and stereoselective reactions of vinyl benzoxazinones with azlactones.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c8cc08962k
Abstract: Under cooperative catalysis of iridium and a Brønsted acid, different C4-substituted azlactones react with vinyl benzoxazinones via a formal [4+2] cycloaddition or substitution reaction in a chemo- and stereoselective mode. Furthermore, the catalytic asymmetric version… read more here.
Keywords: vinyl benzoxazinones; nsted acid; acid cooperatively; cooperatively catalyzed ... See more keywords
Silver-catalyzed chemodivergent assembly of aminomethylated isochromenes and naphthols.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00303a
Abstract: A silver-catalyzed chemodivergent cyclization of alkyne-tethered aldehydes with aminals to aminomethylated 1H-isochromenes and naphthols is described by tuning the reaction conditions. The reaction exhibits broad substrate generality and functional group compatibility. Mechanistic studies have disclosed… read more here.
Keywords: chemodivergent assembly; silver catalyzed; catalyzed chemodivergent; aminomethylated isochromenes ... See more keywords