Cu-Catalyzed Coupling of O-Acyl Oximes with Isatins: Domino Rearrangement Strategy for Direct Access to Quinoline-4-Carboxamides by C-N Bond Cleavage
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201800501
Abstract: A mild domino rearrangement strategy for the direct access to substituted quinoline‐4‐carboxamides has been developed. This copper‐catalyzed coupling reaction of O‐acyl oximes with isatins in the presence of molecular oxygen as the sole oxidizing agent… read more here.
Keywords: strategy direct; quinoline carboxamides; domino rearrangement; direct access ... See more keywords
Recent advances on iron-catalyzed coupling reactions involving organolithium reagents
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2019.05.026
Abstract: Abstract Owing to their inexpensive and environmentally friendly properties, iron-based catalysts have been actively investigated for new organic reactions. In this account, we summarized our recent results on iron-catalyzed cross-coupling reactions and homo-coupling reactions. With… read more here.
Keywords: iron catalyzed; catalyzed coupling; sp3 sp3; recent advances ... See more keywords
Ligand-Controlled Chemoselectivity in Manganese-Catalyzed Coupling of Benzyl Alcohol with Phosphorus Ylide: A Theoretical Study.
Sign Up to like & getrecommendations! Published in 2025 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.5c04327
Abstract: The selective formation of C-C and C═C bonds is fundamentally important in pharmaceutical synthesis and materials science. Herein, the ligand-controlled chemoselectivity of the Mn-catalyzed coupling of benzyl alcohol (BnOH) with a phosphorus ylide for the… read more here.
Keywords: coupling benzyl; ligand controlled; controlled chemoselectivity; ligand ... See more keywords
Rh-Catalyzed Coupling of Acrylic/Benzoic Acids with α-Diazocarbonyl Compounds: An Alternative Route for α-Pyrones and Isocoumarins.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c03992
Abstract: A coupling of acrylic acids/benzoic acids with α-diazocarbonyl compounds has been realized by a combined catalytic system of rhodium catalyst and Zn(OAc)2 additive. The presence of Zn(OAc)2 obviously accelerates the C(sp2)-H activation and destructed the… read more here.
Keywords: benzoic acids; coupling acrylic; acids diazocarbonyl; catalyzed coupling ... See more keywords
Synthesis of Chiral β,β-Disubstituted Ketones via CuH-Catalyzed Coupling of Aryl Alkenes and 3-Aryl-2H-azirines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03311
Abstract: A CuH-catalyzed coupling of aryl alkenes with 3-aryl-2H-azirines has been developed to synthesize optically active β,β-disubstituted ketones. We propose that this protocol occurs through a sequence in which a chiral alkylcopper complex regioselectively attacks the… read more here.
Keywords: disubstituted ketones; coupling aryl; cuh catalyzed; aryl alkenes ... See more keywords
Light-Promoted Nickel-Catalyzed C-O/C-N Coupling of Aryl Halides with Carboxylic Acids and Sulfonamides.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04210
Abstract: A general strategy for the construction of dual-functional carbon-heteroatom bonds has been developed via a light-promoted nickel catalytic system. Employing a simple NiBr2 as the catalyst without any exogeneous ligands and photosensitizers, a variety of… read more here.
Keywords: promoted nickel; coupling aryl; nickel catalyzed; aryl halides ... See more keywords
Silver-Catalyzed Coupling of Ethynylbenziodoxolones with CO2 and Amines to Afford O-β-Oxoalkyl Carbamates.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c01147
Abstract: A novel three-component coupling reaction of ethynylbenziodoxolones (EBXs) with CO2 and amines has been achieved via silver catalysis, thereby providing an efficient method for the construction of a range of structurally diverse and valuable O-β-oxoalkyl… read more here.
Keywords: co2 amines; catalyzed coupling; silver catalyzed; ethynylbenziodoxolones co2 ... See more keywords
Assembly of Biaryl Amines via Mild Copper-Catalyzed Coupling of Anilines with (Hetero)aryl Chlorides/Bromides.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c00004
Abstract: CuI/6-hydroxy picolinohydrazide-catalyzed coupling of (hetero)aryl chlorides with anilines proceeded well at 100 °C to afford biaryl amines in a diverse manner, which represents the first example of Cu-catalyzed biaryl amines under milder conditions. The same… read more here.
Keywords: biaryl amines; catalyzed coupling; aryl chlorides; hetero aryl ... See more keywords
Rh-Catalyzed Coupling of Cyclic 1,3-Dicarbonyl-Derived Iodonium Ylides with Cyclopropanols.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c00598
Abstract: Herein, we report a modular α-monoalkylation of cyclic 1,3-dicarbonyls with cyclopropyl alcohols through a cyclic iodonium ylide strategy. This approach is general, base-free, operationally simple, and suitable for various medically important (hetero)cyclic 1,3-dicarbonyls. A wide… read more here.
Keywords: dicarbonyl derived; coupling cyclic; derived iodonium; catalyzed coupling ... See more keywords
Cobalt-Catalyzed Coupling of Conjugated Dienes and Epoxides with CO.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c01978
Abstract: Here, we report a cobalt-catalyzed coupling of conjugated dienes, epoxides, and CO for a one-step synthesis of dienes adjacent to 1,3-oxygenated motifs. The choice of ligand is crucial for the reaction's effectiveness, while Brønsted acids… read more here.
Keywords: cobalt catalyzed; catalyzed coupling; dienes epoxides; coupling conjugated ... See more keywords
Cu(I)-Catalyzed Coupling and Cycloisomerization of Diazo Compounds with Terminal Yne-Alkylidenecyclopropanes: Synthesis of Functionalized Cyclopenta[ b]naphthalene Derivatives.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b01812
Abstract: A Cu(I)-catalyzed coupling and cycloisomerization of diazo compounds with terminal yne-alkylidenecyclopropanes (ACPs) has been presented. This reaction starts from the formation of an allenic intermediate in the Cu(I)-catalyzed cross-coupling reaction of a diazo compound with… read more here.
Keywords: coupling cycloisomerization; cycloisomerization diazo; yne; cycloisomerization ... See more keywords