Rhodium-Catalyzed (5 + 2) and (5 + 1) Cycloadditions Using 1,4-Enynes as Five-Carbon Building Blocks.
Sign Up to like & getrecommendations! Published in 2019 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.9b00477
Abstract: Cycloaddition reactions are a hallmark in organic synthesis because they provide an efficient way to construct highly substituted carbo- and heterocycles found in natural products and pharmaceutical agents. Most cycloadditions occur under thermal or photochemical… read more here.
Keywords: cycloaddition; carbon; rhodium catalyzed; five carbon ... See more keywords
Copper-Catalyzed Cycloadditions of Diazo Compounds with Imidazolidines/Hexahydropyrimidines for the Syntheses of N-Heterocycles.
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DOI: 10.1021/acs.orglett.2c02561
Abstract: Reported herein are the unprecedented copper-catalyzed formal [n + 1]/[n + 3] (n = 5, 6) cycloadditions of diazo compounds with imidazolidines/hexahydropyrimidines, thus providing a general, economical, and efficient route to construct different sized (six-… read more here.
Keywords: catalyzed cycloadditions; compounds imidazolidines; imidazolidines hexahydropyrimidines; diazo compounds ... See more keywords
Rh-Catalyzed [2 + 2 + 2] Cycloadditions with Benzoquinones: De Novo Access to Naphthoquinones for Lignan and Type II Polyketide Synthesis.
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DOI: 10.1021/acs.orglett.9b04266
Abstract: The first examples of Rh-catalyzed [2 + 2 + 2] cycloadditions between diynes and benzoquinones are described. The method enables de novo and step-economical access to challenging naphthoquinones that are of relevance to lignan and… read more here.
Keywords: type polyketide; polyketide synthesis; lignan type; catalyzed cycloadditions ... See more keywords