Cobalt-Catalyzed Dearomatization of Indoles via Transfer Hydrogenation To Afford Polycyclic Indolines.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c00354
Abstract: A cobalt-catalyzed dearomatization of indoles via transfer hydrogenation with HBpin and H2O has been developed. This reaction offered a straightforward platform to access hexahydropyrido[1,2-a]indoles in high regio- and chemoselectivity. A preliminary reaction mechanism was proposed… read more here.
Keywords: catalyzed dearomatization; via transfer; transfer hydrogenation; cobalt catalyzed ... See more keywords
Enantioselective phosphonation of isoquinolines via chiral phosphoric acid-catalyzed dearomatization.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc02811e
Abstract: An efficient and enantioselective phosphonation protocol for construction of chiral α-aminophosphates and α-aminodiarylphosphine oxides has been developed based on chiral phosphoric acid-catalyzed dearomatization of isoquinolines. A series of chiral 1,2-dihydroisoquinolines with dimethoxy phosphoryl or diphenylphosphono… read more here.
Keywords: enantioselective phosphonation; chiral phosphoric; phosphoric acid; catalyzed dearomatization ... See more keywords
Palladium-Catalyzed Dearomatization of Benzothiophenes: Isolation and Functionalization of a Discrete Dearomatized Intermediate
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DOI: 10.1055/a-2092-9012
Abstract: A Pd-catalyzed decarboxylative dearomatization reaction of of a heterocyclic substrate enables access to an uncommon reaction intermediate, that rearomatizes in the presence of amine bases in a net C–H functionalization sequence. The dearomatized benzo[b]thiophene intermediate… read more here.
Keywords: functionalization; dearomatization; palladium catalyzed; benzothiophenes isolation ... See more keywords