Rhodium-Catalyzed Denitrogenative Diazole-Triazole Coupling toward Aza-Bridged Structures and Imidazole-Based Chelating Ligands.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01092
Abstract: 1,4,8-Triazaocta-1,3,5,7-tetraenes, generated in situ by Rh2(Piv)4-catalyzed denitrogenative coupling of pyrazoles with 1-sulfonyl-1,2,3-triazoles, smoothly form 2,6,8-triazabicyclo[3.2.1]octa-3,6-dienes via intramolecular aza-Diels-Alder cycloaddition. This domino reaction, combined with the subsequent thermal or acid-catalyzed rearrangement of the cycloadducts, provides direct… read more here.
Keywords: catalyzed denitrogenative; rhodium catalyzed; diazole triazole; triazole coupling ... See more keywords
Rh(II)-catalyzed Denitrogenative Cascade of 1,2,3-Triazolyl Propiolates and Indoles: Access to Butenolide Tethered Homotryptamines.
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DOI: 10.1021/acs.orglett.1c01215
Abstract: An efficient Rh(II)-catalyzed denitrogenative reaction of indoles with 1,2,3-triazolyl propiolates has been developed. This methodology provides facile access to butenolide tethered homotryptamines in good to excellent yields under operationally simple conditions and features a broad… read more here.
Keywords: catalyzed denitrogenative; butenolide tethered; access butenolide; triazolyl propiolates ... See more keywords
Nickel-Catalyzed Denitrogenative Cyclization of 1,2,3,4-Benzothiatriazin-1,1(2H)-dioxides with Arynes To Synthesize Biaryl Sultams.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00920
Abstract: Herein, we report the nickel-catalyzed denitrogenative cyclization reaction of 1,2,3,4-benzothiatriazine-1,1-dioxides with arynes to generate the polysubstituted biaryl sultams with tolerance of a wide diversity of substituents on every subunit. The mechanistic study indicates that the… read more here.
Keywords: nickel catalyzed; catalyzed denitrogenative; cyclization; biaryl sultams ... See more keywords
Indium-Catalyzed Denitrogenative Transannulation of Pyridotriazoles: Synthesis of Pyrido[1,2- a]indoles.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b00180
Abstract: Pyrido[1,2- a]indoles are known for medicinally and pharmaceutically important compounds; however, the efficient synthetic routes are scarce in the literature. We report herein a convenient and efficient route to synthesize these molecules through indium-catalyzed transannulation… read more here.
Keywords: catalyzed denitrogenative; pyrido indoles; transannulation pyridotriazoles; denitrogenative transannulation ... See more keywords
Rhodium-catalyzed denitrogenative transannulation of 1,2,3-triazolyl-carbamates: efficient access to 4-aminooxazolidinones
Sign Up to like & getrecommendations! Published in 2017 at "Organic chemistry frontiers"
DOI: 10.1039/c7qo00101k
Abstract: Herein we describe a novel Rh(II)-catalyzed intramolecular transannulation reaction of 1,2,3-triazolyl carbamates to access functionalized 4-aminooxazolidinones under operationally simple conditions with low catalyst loadings. A one-pot tandem Cu(I)-catalyzed synthesis of 1,2,3-triazolyl-carbamates from propargyl carbamates followed… read more here.
Keywords: catalyzed denitrogenative; transannulation; rhodium catalyzed; triazolyl carbamates ... See more keywords
Rh(ii)-Catalyzed denitrogenative 1-sulfonyl-1,2,3-triazole-1-alkyl-1,2,3-triazole cross-coupling as a route to 3-sulfonamido-1H-pyrroles and 1,2,3-triazol-3-ium ylides
Sign Up to like & getrecommendations! Published in 2021 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo01571g
Abstract: A method for the synthesis of 1-alkyl-3-sulfonamido-1H-pyrroles by the Rh(II)-catalyzed denitrogenative coupling of two different types of 1,2,3-triazoles, 1-alkyl-4-aryl- and 1-sulfonyl-4-aryl-1,2,3-triazoles, has been developed. According to the DFT calculations, the reaction proceeds via the attack… read more here.
Keywords: triazole; catalyzed denitrogenative; sulfonamido pyrroles; alkyl ... See more keywords