N-Heterocyclic carbene catalyzed desymmetrization of diols: access to enantioenriched oxindoles having a C3-quaternary stereocenter.
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DOI: 10.1039/d3cc00489a
Abstract: Herein, we describe an effective strategy for enantioselective synthesis of oxindoles having a C3-quaternary stereocenter via N-heterocyclic carbene (NHC) catalyzed desymmetrization of diols. The process is based on the catalytic asymmetric transfer acylation of primary… read more here.
Keywords: catalyzed desymmetrization; quaternary stereocenter; desymmetrization diols; oxindoles quaternary ... See more keywords