Lanthanum-Catalyzed Double Hydrophosphinylation of Nitriles
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DOI: 10.1021/acs.organomet.6b00919
Abstract: A new lanthanum-based catalyst was shown to be effective for the double hydrophosphinylation of unactivated nitriles under very mild conditions. Surprisingly, the lanthanum catalyst gave two regioisomeric products depending on the nature of the starting… read more here.
Keywords: addition; catalyzed double; lanthanum catalyzed; hydrophosphinylation ... See more keywords
Rh(III)-Catalyzed Double C-H Functionalization of Indoles with Cyclopropenones via Sequential C-H/C-C/C-H Bond Activation.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c01292
Abstract: An unprecedented Rh(III)-catalyzed double C-H functionalization of indoles with cyclopropenones via sequential C-H/C-C/C-H bond activation has been developed. This procedure represents the first example for assembling of cyclopenta[b]indoles utilizing cyclopropenones as 3C synthons. This powerful… read more here.
Keywords: functionalization indoles; indoles cyclopropenones; double functionalization; catalyzed double ... See more keywords
A Four-Step Synthesis of (±)-γ-Lycorane via Pd0-Catalyzed Double C(sp2)-H/C(sp3)-H Arylation.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.7b03909
Abstract: An expedient synthesis of lycorine alkaloids is reported using a palladium(0)-catalyzed double C-X/C-H arylation as the key step. The selectivity of this reaction was controlled through the judicious choice of the two halogen atoms, and… read more here.
Keywords: catalyzed double; step; arylation; synthesis lycorane ... See more keywords
Direct synthesis of annulated indoles through palladium-catalyzed double alkylations
Sign Up to like & getrecommendations! Published in 2020 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo00135j
Abstract: A facile, one-step synthesis of annulated indoles from (N–H) indoles and dibromoalkanes was developed through a palladium-catalyzed double alkylation process. The reaction proceeds through a palladium-catalyzed norbornene-mediated C2-alkylation of indoles and subsequent regioselective cyclization. The… read more here.
Keywords: annulated indoles; catalyzed double; palladium catalyzed; synthesis annulated ... See more keywords