Glycosyl hydrolase catalyzed glycosylation in unconventional media.
Sign Up to like & getrecommendations! Published in 2020 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-020-10924-1
Abstract: The reversible hydrolytic property of glycosyl hydrolases (GHs) as well as their acceptance of aglycones other than water has provided the abilities of GHs in synthesizing glycosides. Together with desirable physiochemical properties of glycosides and… read more here.
Keywords: glycosyl hydrolase; organic solvents; water; catalyzed glycosylation ... See more keywords
One-Pot Stereoselective Synthesis of 2,3-Diglycosylindoles and Tryptophan-C-glycosides via Palladium-Catalyzed C-H Glycosylation of Indole and Tryptophan.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00602
Abstract: We described a novel palladium-catalyzed C-H glycosylation of indole or tryptophan for a one-pot stereoselective synthesis of 2,3-diglycosylindoles and tryptophan-C-glycosides. In this strategy, the use of air and base-free and ligand-free conditions provided a highly… read more here.
Keywords: glycosylation indole; pot stereoselective; catalyzed glycosylation; palladium catalyzed ... See more keywords
Synthesis of Nucleosides and Deoxynucleosides via Gold(I)-Catalyzed N-Glycosylation of Glycosyl (Z)-Ynenoates.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03964
Abstract: Nucleoside analogues are widely used as anticancer and antiviral drugs. Here, we develop a highly efficient gold(I)-catalyzed N-glycosylation approach for versatile synthesis of various types of nucleosides and deoxynucleosides with glycosyl (Z)-ynenoates as donors. The… read more here.
Keywords: nucleosides deoxynucleosides; catalyzed glycosylation; synthesis; glycosylation ... See more keywords
A Cu(OTf)2-Catalyzed Glycosylation with Glycosyl ortho-N-Phthalimidoylpropynyl Benzoates as Donors.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c01163
Abstract: A Cu(OTf)2-catalyzed glycosylation protocol using glycosyl ortho-N-phthalimidoylpropynyl benzoates (NPPBs) as donors was disclosed, which features an inexpensive copper catalyst, operationally convenient conditions, high to excellent yields, and a broad substrate scope. Mechanistic studies indicated an… read more here.
Keywords: catalyzed glycosylation; otf catalyzed; glycosyl ortho; phthalimidoylpropynyl benzoates ... See more keywords
Probing the stereoselectivity of OleD-catalyzed glycosylation of cardiotonic steroids
Sign Up to like & getrecommendations! Published in 2018 at "RSC Advances"
DOI: 10.1039/c7ra11979h
Abstract: The glycosyltransferase OleD variant as a catalyst for the glycosylation of four pairs of epimers of cardiotonic steroids (CTS) are assessed. The results of this study demonstrated that the OleD-catalyze glycosylation of CTS is significantly… read more here.
Keywords: oled catalyzed; probing stereoselectivity; catalyzed glycosylation; stereoselectivity oled ... See more keywords
Palladium Catalyzed C-H Glycosylation and Retro Diels-Alder Tandem Reaction via Structurally Modified Norbornadiene (smNBDs)
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Science"
DOI: 10.1039/d1sc03569j
Abstract: This report describes palladium catalyzed C-H glycosylation and retro Diels-Alder tandem reaction via structurally modified norbornadiene (smNBDs). The smNBDs was proposed to regulate the reactivity of aryl-norbornadiene-palladacycle (ANP) process, as... read more here.
Keywords: glycosylation retro; diels alder; catalyzed glycosylation; retro diels ... See more keywords