Theoretical study of the [3 + 4] annulation reaction of 2-bromoenals with malonates catalyzed by N-heterocyclic carbene
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Catalysis"
DOI: 10.1016/j.mcat.2021.111647
Abstract: Abstract A systematic density functional theory (DFT) computation has been performed to understand the mechanism and stereoselectivity involved in the [3 + 4] annulation reaction between 2-bromoenal and 3-formylindol-2-methyl-malonate catalyzed by N-heterocyclic carbene (NHC). The optimal reaction… read more here.
Keywords: annulation reaction; reaction; heterocyclic carbene; catalyzed heterocyclic ... See more keywords
Diastereodivergent Enantioselective [8 + 2] Annulation of Tropones and Enals Catalyzed by N-Heterocyclic Carbenes.
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DOI: 10.1021/acs.orglett.9b00906
Abstract: N-Heterocyclic carbene catalysts are used for the first time to mediate asymmetric [8 + 2] cycloadditions of enals with tropones. The kinetic [8 + 2] cis-cycloadducts can be epimerized to their trans analogues by simply… read more here.
Keywords: diastereodivergent enantioselective; catalyzed heterocyclic; enals catalyzed; tropones enals ... See more keywords
π-Extension of heterocycles via a Pd-catalyzed heterocyclic aryne annulation: π-extended donors for TADF emitters
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DOI: 10.1039/d2sc01788a
Abstract: We report the annulation of heterocyclic building blocks to access π-extended polycyclic aromatic hydrocarbons (PAHs). The method involves the trapping of short-lived hetarynes with catalytically-generated biaryl palladium intermediates and allows for the concise appendage of… read more here.
Keywords: extension heterocycles; heterocycles via; catalyzed heterocyclic; via catalyzed ... See more keywords