Palladium-Catalyzed Hydrocarbonylative Spirolactonization for Expedite Construction of Oxaspirolactones.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00019
Abstract: A novel palladium-catalyzed cascade hydrocarbonylation of the alkene moiety followed by intramolecular spirolactonization of 2-vinylaryl hydroxyalkyl ketones has been developed, which offers efficient and expedited access to furnishing oxaspirolactones in high yields with high chemoselectivities.… read more here.
Keywords: hydrocarbonylative spirolactonization; spirolactonization; palladium catalyzed; expedite construction ... See more keywords
Synthesis of Allylic Alcohols via Cu-Catalyzed Hydrocarbonylative Coupling of Alkynes with Alkyl Halides.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b12582
Abstract: We have developed a modular procedure to synthesize allylic alcohols from tertiary, secondary, and primary alkyl halides and alkynes via a Cu-catalyzed hydrocarbonylative coupling and 1,2-reduction tandem sequence. The use of tertiary alkyl halides as… read more here.
Keywords: alkyl halides; hydrocarbonylative coupling; catalyzed hydrocarbonylative; via catalyzed ... See more keywords