Rhodium-Catalyzed O-H Insertion Reactions to (2-Diazo-1,1,3,3,3-pentafluoropropyl)phosphonate: A Convenient Route to Fluorinated β-Alkoxy Vinylphosphonates.
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DOI: 10.1021/acs.orglett.5c04281
Abstract: The rhodium(II)-catalyzed insertion of benzyl and alkyl alcohols with 2-diazo-1,1,3,3,3-pentafluoropropylphosphonate unexpectedly afforded fluorinated β-alkoxy vinylphosphonates. The reaction proceeds under mild conditions and shows broad substrate scope. Twenty-four new derivatives were synthesized in moderate to excellent… read more here.
Keywords: phosphonate; catalyzed insertion; rhodium catalyzed; alkoxy vinylphosphonates ... See more keywords
Fe-Catalyzed insertion of fluoromethylcarbenes generated from sulfonium salts into X–H bonds (X = Si, C, P)
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DOI: 10.1039/c7qo00430c
Abstract: The Fe-catalyzed insertion of fluoromethylcarbenes including trifluoromethylcarbene and difluoromethylcarbene generated in situ from sulfonium salts (Ph2S+CH2CF3−OTf and Ph2S+CH2CF2H −OTf) into X–H (X = Si, C and P) bonds is described. The insertion of both carbenes… read more here.
Keywords: sulfonium salts; catalyzed insertion; insertion; fluoromethylcarbenes generated ... See more keywords
Entry to new spiroheterocycles via tandem Rh(II)-catalyzed O–H insertion/base-promoted cyclization involving diazoarylidene succinimides
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DOI: 10.3762/bjoc.20.48
Abstract: A facile approach to novel medicinally relevant spiro heterocyclic scaffolds (namely furan-2(5H)-ones, tetrahydrofurans and pyrans spiro-conjugated with the succinimide ring) has been developed. The protocol consists of Rh(II)-catalyzed insertion of heterocyclic carbenes derived from diazoarylidene… read more here.
Keywords: base promoted; diazoarylidene succinimides; promoted cyclization; catalyzed insertion ... See more keywords