Silver(I) catalyzed intermolecular alkene carbo-alkoxylation through cleavage of allylic ether C–O bond
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2020.151895
Abstract: Abstract All rights reserved. First example of allylic ether’s dimerization reaction was developed through olefin’s C–O bond insertion via Ag(I) catalysis. Other aromatic olefins, such as styrene and its electro-poor analogues could participate to provide… read more here.
Keywords: silver catalyzed; allylic ether; catalyzed intermolecular; bond ... See more keywords
Palladium(0)-Catalyzed Intermolecular Asymmetric Allylic Dearomatization of Substituted β-Naphthols with Morita-Baylis-Hillman (MBH) Adducts.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03262
Abstract: Pd-catalyzed intermolecular asymmetric allylic dearomatization of substituted β-naphthol derivatives with Boc-protected Morita-Baylis-Hillman (MBH) adducts was developed. The reaction occurs smoothly in 1,4-dioxane at room temperature in the presence of [Pd(C3H5)Cl]2 (2.5 mol %), (S, Sp)-PHOX… read more here.
Keywords: morita baylis; allylic dearomatization; intermolecular asymmetric; catalyzed intermolecular ... See more keywords
Gold-Catalyzed Intermolecular Alkyne Insertion into the N-S Bond in Sulfenamides.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03831
Abstract: Gold-catalyzed reactions between sulfenamides and terminal alkynes proceeded via cis-insertion of alkynes into the N-S bond in sulfenamides, affording the corresponding β-sulfenylenamines in yields up to 90%. Mechanistic studies revealed that the reactions proceeded via… read more here.
Keywords: bond sulfenamides; catalyzed intermolecular; insertion; gold catalyzed ... See more keywords
Pd(0)-Catalyzed Intermolecular Dearomatizing [3 + 2] Spiroannulation of Phenol-Based Biaryls and Allenes.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00014
Abstract: Readily available phenol-derived biaryls reacted with allenes under palladium catalysis to provide a variety of highly valuable spiro[cyclohexane-1,1'-indene]-2,5-dien-4-ones. This new catalytic process, involving a key step of regioselective allylative dearomatization of phenol, proceeded efficiently through… read more here.
Keywords: catalyzed intermolecular; intermolecular dearomatizing; spiroannulation phenol; phenol based ... See more keywords
Photoredox-Catalyzed Intermolecular Remote C-H and C-C Vinylation via Iminyl Radicals.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b02540
Abstract: A unified strategy for intermolecular remote C(sp3)-H and C-C vinylation of O-acyl oximes with vinyl boronic acids has been achieved. This strategy is enabled by photoreductive generation of iminyl radicals from O-acyl oximes under irradiation… read more here.
Keywords: vinylation; catalyzed intermolecular; remote vinylation; iminyl radicals ... See more keywords
Copper-Catalyzed Intermolecular Carboamination of Alkenes Induced by Visible Light.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b00252
Abstract: A photoinduced copper-catalyzed three-component reaction involving carbohalide, alkene and amine has been developed, leading to valuable fluoroalkyl-containing amines. A sole inexpensive CuCl is used as the photo- and coupling catalyst. A broad array of substrates… read more here.
Keywords: catalyzed intermolecular; induced visible; intermolecular carboamination; carboamination alkenes ... See more keywords
Copper-Catalyzed Intermolecular [4 + 2] Annulation Enabled by Internal Oxidant-Promoted C(sp3)-H Functionalization: Access to 3-Trifluoromethylated 3-Hydroxy-cyclohexan-1-ones.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b01817
Abstract: A copper-catalyzed diastereoselective [4 + 2] cyclolization of α,β-unsaturated ketoxime acetates and trifluoromethyl ketones affords various 3-trifluoromethylated 3-hydroxy-cylcohexan-1-ones smoothly. This reaction features the selective functionalization of a less acidic C(sp3)-H bond by an internal oxdative… read more here.
Keywords: catalyzed intermolecular; trifluoromethylated hydroxy; sp3 functionalization; internal oxidant ... See more keywords
Cobalt-Catalyzed Intermolecular Markovnikov Hydroamination of Nonactivated Olefins: N2-Selective Alkylation of Benzotriazole.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.9b04375
Abstract: Cobalt-catalyzed Markovnikov-selective hydroamination of nonactivated olefins was developed. Hydrogen atom transfer from a catalytically generated cobalt(III)-hydride complex to the olefins proceeded regioselectively, and the nucleophilic addition of benzotriazoles occurred selectively at their N2-positions. The synthetic… read more here.
Keywords: nonactivated olefins; catalyzed intermolecular; intermolecular markovnikov; cobalt catalyzed ... See more keywords
Nickel-Catalyzed Intermolecular Carbobromination of Alkynes
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DOI: 10.1021/acscatal.0c00980
Abstract: Organohalogen compounds such as alkenyl bromides are versatile and essential building blocks in organic synthesis. Herein, we describe the nickel-catalyzed intermolecular carbobrominations of alkyn... read more here.
Keywords: intermolecular carbobromination; carbobromination alkynes; catalyzed intermolecular; nickel catalyzed ... See more keywords
Palladium-Catalyzed Intermolecular Trans-Selective Carbofunctionalization of Internal Alkynes to Highly Functionalized Alkenes
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DOI: 10.1021/acscatal.0c02522
Abstract: A palladium/DPEphos-catalyzed intermolecular trans-selective carbofunctionalization of internal alkynes has been established herein. This method proceeds through a formal anti-carbopalladation, for... read more here.
Keywords: catalyzed intermolecular; internal alkynes; intermolecular trans; selective carbofunctionalization ... See more keywords
Ruthenium-catalyzed Intermolecular Coupling of Vinylic 1,2-Bisboronates with Alkynes: Stereoselective Access to Boryl-Substituted Homoallylic Alcohols.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c01755
Abstract: The ruthenium catalytic addition of alkenes to alkynes has been demonstrated as a powerful synthetic tool to form diene motifs and widely applied in the synthesis of complex molecules. How-ever, except for the intramolecular coupling,… read more here.
Keywords: substituted homoallylic; boryl substituted; ruthenium catalyzed; catalyzed intermolecular ... See more keywords