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   Articles with "catalyzed kinetic" as a keyword



Asymmetric Synthesis of Dihydropyranones with Three Contiguous Stereocenters by an NHC‐Catalyzed Kinetic Resolution

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recommendations! Published in 2021 at "European Journal of Organic Chemistry"

DOI: 10.1002/ejoc.202100491

Abstract: An oxidative NHC-catalyzed kinetic resolution (KR) of racemic mixtures is presented. The developed reaction furnishes tricyclic dihydropyranones with three contiguous stereocenters in excellent dia- and enantioselectivity, with good-to-moderate yields. Mechanistic studies indicate that the rate-determining… read more here.

Keywords: three contiguous; kinetic resolution; dihydropyranones three; catalyzed kinetic ... See more keywords
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Chemoenzymatic enantioselective and stereo-convergent syntheses of lisofylline enantiomers via lipase-catalyzed kinetic resolution and optical inversion approach

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recommendations! Published in 2021 at "Molecular Catalysis"

DOI: 10.1016/j.mcat.2021.111451

Abstract: Abstract Highly enantioselective enzymatic kinetic resolution (EKR) of racemic lisofylline is presented for the first time. A comprehensive optimization of the key parameters of lipase-catalyzed transesterification of racemic lisofylline revealed that optimal biocatalytic system consisted… read more here.

Keywords: resolution; kinetic resolution; catalyzed kinetic; racemic lisofylline ... See more keywords
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Ag(I)-Catalyzed Kinetic Resolution of Cyclopentene-1,3-diones.

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recommendations! Published in 2018 at "Organic letters"

DOI: 10.1021/acs.orglett.8b01254

Abstract: An efficient kinetic resolution of readily available racemic cyclopentene-1,3-diones has been developed via a Ag(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides. This methodology shows good functional-group tolerance, delivering an array of synthetically valuable cyclopentene-1,3-diones with… read more here.

Keywords: resolution; kinetic resolution; cyclopentene diones; catalyzed kinetic ... See more keywords
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Base-promoted lipase-catalyzed kinetic resolution of atropisomeric 1,1′-biaryl-2,2′-diols

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recommendations! Published in 2019 at "RSC Advances"

DOI: 10.1039/c8ra09070j

Abstract: The addition of a stoichiometric amount of Na2CO3 dramatically accelerates the lipase-catalyzed kinetic resolution of a range of atropisomeric 1,1′-biaryl-2,2′-diols. read more here.

Keywords: kinetic resolution; biaryl diols; catalyzed kinetic; atropisomeric biaryl ... See more keywords