Palladium-catalyzed nucleomethylation of alkynes for synthesis of methylated heteroaromatic compounds
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DOI: 10.1039/d2sc03294e
Abstract: Herein, we disclosed a novel and efficient palladium-catalyzed nucleomethylation of alkynes for the simultaneous construction of the heteroaromatic ring and methyl group. The 3-methylindoles, 3-methylbenzofurans and 4-methylisoquinolines were obtained in moderate to excellent yields. Notably,… read more here.
Keywords: catalyzed nucleomethylation; palladium catalyzed; nucleomethylation alkynes; alkynes synthesis ... See more keywords