Palladium-Catalyzed Nucleophilic Reaction of Alkylidenecyclopropanes with β,γ-Unsaturated α-Ketoesters: Ligand-Controlled Divergent Synthesis.
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DOI: 10.1021/acs.orglett.2c02839
Abstract: A palladium-catalyzed ligand-controlled selective 1,4-addition and cycloaddition reaction of β,γ-unsaturated α-ketoesters with alkylidenecyclopropanes (ACPs) has been developed. Using ACPs and β,γ-unsaturated α-ketoesters as starting materials, γ-dienyl-α-ketoesters and dihydro-2H-pyrans could be prepared selectively by modulating the… read more here.
Keywords: catalyzed nucleophilic; unsaturated ketoesters; palladium catalyzed; ligand controlled ... See more keywords
Ag(I)-Catalyzed Nucleophilic Addition and Friedel-Crafts Alkylation between α-Oxoketene Dithioacetals and Propargyl Carbonates.
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DOI: 10.1021/acs.orglett.8b03180
Abstract: Silver-catalyzed nucleophilic addition and intramolecular Friedel-Crafts alkylation between α-oxoketene dithioacetals and tertiary propargylic carbonates have been realized. The reactions proceeded in moderate to good yields with broad substrate scope, providing a straightforward method for the… read more here.
Keywords: crafts alkylation; catalyzed nucleophilic; nucleophilic addition; alkylation oxoketene ... See more keywords
Formamide-Catalyzed Nucleophilic Substitutions: Mechanistic Insight and Rationalization of Catalytic Activity
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DOI: 10.1021/acscatal.0c03348
Abstract: Herein, detailed mechanistic investigations into formamide-catalyzed nucleophilic substitution (SN) of alcohols are reported. Alkoxyiminium chlorides and hexafluorophosphates were synthesized and c... read more here.
Keywords: catalyzed nucleophilic; mechanistic insight; formamide catalyzed; insight rationalization ... See more keywords
Palladium-Catalyzed Nucleophilic Isocyanation for the Synthesis of α-Aryl-α-isocyanoacetoamide Derivatives
Sign Up to like & getrecommendations! Published in 2021 at "Bulletin of the Chemical Society of Japan"
DOI: 10.1246/bcsj.20210214
Abstract: α-Aryl-α-isocyanoacetoamide derivatives were synthesized through palladium-catalyzed nucleophilic isocyanation. Diethylphosphates derived from N,N-disubstituted mandelamide derivatives reacted with... read more here.
Keywords: nucleophilic isocyanation; catalyzed nucleophilic; isocyanoacetoamide derivatives; aryl isocyanoacetoamide ... See more keywords