Cu-Catalyzed Regio- and Stereodivergent Chemoselective sp/sp 1,3- and 1,4-Diborylations of CF3-Containing 1,3-Enynes
Sign Up to like & getrecommendations! Published in 2020 at "Chem"
DOI: 10.1016/j.chempr.2020.06.034
Abstract: Summary CF3-containing multi-borylated compounds are intriguing molecules that can serve as building blocks and readily transform into various significant molecules. Here, a series of Cu-catalyzed assembly of 1,3- and 1,4-diborylated compounds bearing CF3 group starting… read more here.
Keywords: catalyzed regio; cf3 containing; regio stereodivergent; cf3 group ... See more keywords
Cu-catalyzed regio- and stereoselective sulfonylation of multi-substituted allenes
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2018.12.031
Abstract: Abstract Regio- and stereoselective sulfonylation of allenes under Cu catalysis is described. Allenyl sp carbons exclusively react with TsCN to give the corresponding alkenyl sulfones. The reaction is initiated by addition of tosyl radical to… read more here.
Keywords: multi substituted; catalyzed regio; regio stereoselective; sulfonylation multi ... See more keywords
Ligand-Enabled Copper-Catalyzed Regio- and Stereoselective Allylboration of 1-Trifluoromethylalkenes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03024
Abstract: A copper-catalyzed regio- and stereoselective allylboration of 1-trifluoromethylalkenes with bis(pinacolato)diboron (pinB-Bpin) and allylic chlorides has been developed to form functionalized trifluoromethylated products with high diastereoselectivity. The key to success is the judicious choice of Cs2CO3… read more here.
Keywords: stereoselective allylboration; catalyzed regio; allylboration trifluoromethylalkenes; regio stereoselective ... See more keywords
Silylium-Catalyzed Regio- and Stereoselective Carbosilylation of Ynamides with Allylic Trimethylsilanes
Sign Up to like & getrecommendations! Published in 2023 at "Organic Letters"
DOI: 10.1021/acs.orglett.3c00221
Abstract: The regio- and stereoselective carbosilylation of tosylynamides with allylic trimethylsilanes takes place under mild conditions in the presence of catalytic TMSNTf2 or HNTf2 to give (Z)-α-allyl-β-trimethylsilylenamides with good yields. Theoretical calculations show the activation of… read more here.
Keywords: catalyzed regio; stereoselective carbosilylation; regio stereoselective; allylic trimethylsilanes ... See more keywords
Copper-Catalyzed Regio- and Stereoselective Iodocyanation and Dicyanation of Alkynes with Cyanogen Iodide.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b01378
Abstract: anti-Selective iodocyanation and dicyanation of various internal alkynes has been developed by means of a simple copper catalyst system. The selectivity of the products was switched by tuning the reaction conditions. Mechanistic studies have revealed… read more here.
Keywords: catalyzed regio; iodocyanation; iodocyanation dicyanation; regio stereoselective ... See more keywords
Copper-Catalyzed Regio- and Diastereoselective Additions of Boron-Stabilized Carbanions to Heteroarenium Salts: Synthesis of Azaheterocycles Containing Contiguous Stereocenters
Sign Up to like & getrecommendations! Published in 2020 at "ACS Catalysis"
DOI: 10.1021/acscatal.0c04474
Abstract: Nucleophilic addition of diborylalkyl reagents to N-alkyl or N-acylpyridinium and related heteroarenium salts has been developed as a key step for the synthesis of nonaromatic nitrogen heterocycles... read more here.
Keywords: heteroarenium; catalyzed regio; regio diastereoselective; heteroarenium salts ... See more keywords
d-Glucosamine as the Green Ligand for Cu(I)-Catalyzed Regio- and Stereoselective Domino Synthesis of (Z)-3-Methyleneisoindoline-1-ones and (E)-N-Aryl-4H-thiochromen-4-imines
Sign Up to like & getrecommendations! Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c03003
Abstract: d-Glucosamine, a natural, inexpensive, and conveniently accessible sugar, has been explored as an efficient ligand for the Cu(I)-catalyzed regio- and stereoselective synthesis of an array of (Z)-3-methyleneisoindoline-1-ones and (E)-N-aryl-4H-thiochromen-4-imines in good-to-excellent yield in a tandem… read more here.
Keywords: ligand catalyzed; catalyzed regio; reaction; regio stereoselective ... See more keywords
Rh-Catalyzed Regio- and Enantioselective Allylic Phosphinylation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c00239
Abstract: Transition-metal-catalyzed branched and enantioselective allylic substitution of monosubstituted precursors with carbon, nitrogen, oxygen, sulfur, and fluoride nucleophiles has been well-established. However, such a selective carbon-phosphorus bond formation has not been realized probably due to the… read more here.
Keywords: phosphine; catalyzed regio; allylic phosphinylation; enantioselective allylic ... See more keywords
Nickel-Catalyzed Regio- and Enantioselective Hydroamination of Unactivated Alkenes Using Carbonyl Directing Groups.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c02343
Abstract: The asymmetric addition of an N-H bond to various alkenes via a direct catalytic method is a powerful way of synthesizing value-added chiral amines. Therefore, the enantio- and regioselective hydroamination of unactivated alkenes remains an… read more here.
Keywords: enantio regioselective; hydroamination unactivated; catalyzed regio; nickel catalyzed ... See more keywords
Cobalt-Catalyzed Regio- and Enantioselective Allylic Amination.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b06035
Abstract: The first earth-abundant cobalt-catalyzed highly branched- and enantioselective allylic amination of racemic branched allylic car-bonates bearing alkyl groups with both aromatic and aliphatic amines have been developed. The process allows rapid access of allylic amines… read more here.
Keywords: catalyzed regio; enantioselective allylic; allylic amination; cobalt catalyzed ... See more keywords
Pd-Catalyzed regio- and enantioselective allylic substitution with 2-pyridones.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc07482a
Abstract: An efficient method for the asymmetric synthesis of N-substituted 2-pyridones via Pd-catalyzed regio- and enantioselective allylic substitution of hydroxyl-containing allylic carbonates with 2-pyridones has been developed. By using a palladium complex in situ generated from… read more here.
Keywords: catalyzed regio; regio enantioselective; substitution pyridones; enantioselective allylic ... See more keywords