Advances in Organoboron‐Catalyzed Regio‐ and Stereoselective Glycosylation
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DOI: 10.1002/ejoc.202500552
Abstract: The efficient and stereoselective formation of glycosidic bonds remains a long‐standing challenge in carbohydrate chemistry, particularly in the synthesis of complex glycans, while conventional chemical methods often involve metal‐based catalysts and require harsh reaction conditions,… read more here.
Keywords: regio stereoselective; organoboron catalyzed; chemistry; catalyzed regio ... See more keywords
Cu-Catalyzed Regio- and Stereodivergent Chemoselective sp/sp 1,3- and 1,4-Diborylations of CF3-Containing 1,3-Enynes
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DOI: 10.1016/j.chempr.2020.06.034
Abstract: Summary CF3-containing multi-borylated compounds are intriguing molecules that can serve as building blocks and readily transform into various significant molecules. Here, a series of Cu-catalyzed assembly of 1,3- and 1,4-diborylated compounds bearing CF3 group starting… read more here.
Keywords: catalyzed regio; cf3 containing; regio stereodivergent; cf3 group ... See more keywords
Cu-catalyzed regio- and stereoselective sulfonylation of multi-substituted allenes
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DOI: 10.1016/j.tet.2018.12.031
Abstract: Abstract Regio- and stereoselective sulfonylation of allenes under Cu catalysis is described. Allenyl sp carbons exclusively react with TsCN to give the corresponding alkenyl sulfones. The reaction is initiated by addition of tosyl radical to… read more here.
Keywords: multi substituted; catalyzed regio; regio stereoselective; sulfonylation multi ... See more keywords
Ligand-Enabled Copper-Catalyzed Regio- and Stereoselective Allylboration of 1-Trifluoromethylalkenes.
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DOI: 10.1021/acs.orglett.2c03024
Abstract: A copper-catalyzed regio- and stereoselective allylboration of 1-trifluoromethylalkenes with bis(pinacolato)diboron (pinB-Bpin) and allylic chlorides has been developed to form functionalized trifluoromethylated products with high diastereoselectivity. The key to success is the judicious choice of Cs2CO3… read more here.
Keywords: stereoselective allylboration; catalyzed regio; allylboration trifluoromethylalkenes; regio stereoselective ... See more keywords
Silylium-Catalyzed Regio- and Stereoselective Carbosilylation of Ynamides with Allylic Trimethylsilanes
Sign Up to like & getrecommendations! Published in 2023 at "Organic Letters"
DOI: 10.1021/acs.orglett.3c00221
Abstract: The regio- and stereoselective carbosilylation of tosylynamides with allylic trimethylsilanes takes place under mild conditions in the presence of catalytic TMSNTf2 or HNTf2 to give (Z)-α-allyl-β-trimethylsilylenamides with good yields. Theoretical calculations show the activation of… read more here.
Keywords: catalyzed regio; stereoselective carbosilylation; regio stereoselective; allylic trimethylsilanes ... See more keywords
Iridium-Catalyzed Regio- and Enantioselective N-Allylation of Pyrazoles with Dienyl/Monoallylic Alcohols.
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DOI: 10.1021/acs.orglett.4c01201
Abstract: Here we report the first example of iridium-catalyzed asymmetric N-allylation of pyrazoles with dienyl allylic alcohols under mild conditions with broad functional group tolerance, exhibiting excellent N1/C3-site selectivities and enantioselectivities (up to >99% ee). In… read more here.
Keywords: catalyzed regio; iridium catalyzed; allylation pyrazoles; regio enantioselective ... See more keywords
Palladium-Catalyzed Regio- and Diastereoselective Hydro(hetero)arylation for Rapid Construction of Quaternary Center Containing Cyclobutanes.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c02645
Abstract: Herein we report a Pd-catalyzed regio- and diastereoselective hydro(hetero)arylation of inactivated alkylidenecyclobutanes. This protocol provides a rapid and atom-economical route to access 3-cyclobutyl (hetero)arenes with good functionalities toleration. With the assistance of the directing group,… read more here.
Keywords: hetero arylation; catalyzed regio; hydro hetero; diastereoselective hydro ... See more keywords
Cobalt-Catalyzed Regio-, Diastereo-, and Enantioselective Reductive Coupling of Internal Alkynes with Cyclobutenes.
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DOI: 10.1021/acs.orglett.5c01695
Abstract: Herein, we report the cobalt-catalyzed asymmetric ene-yne reductive coupling of internal alkynes and unactivated cyclobutenes. The reaction produced densely functionalized chiral vinyl cyclobutanes in up to 92% yields with excellent absolute and relative stereocontrol (>99%… read more here.
Keywords: catalyzed regio; coupling internal; reductive coupling; cobalt catalyzed ... See more keywords
Copper-Catalyzed Regio- and Stereoselective Iodocyanation and Dicyanation of Alkynes with Cyanogen Iodide.
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DOI: 10.1021/acs.orglett.7b01378
Abstract: anti-Selective iodocyanation and dicyanation of various internal alkynes has been developed by means of a simple copper catalyst system. The selectivity of the products was switched by tuning the reaction conditions. Mechanistic studies have revealed… read more here.
Keywords: catalyzed regio; iodocyanation; iodocyanation dicyanation; regio stereoselective ... See more keywords
Copper-Catalyzed Regio- and Diastereoselective Additions of Boron-Stabilized Carbanions to Heteroarenium Salts: Synthesis of Azaheterocycles Containing Contiguous Stereocenters
Sign Up to like & getrecommendations! Published in 2020 at "ACS Catalysis"
DOI: 10.1021/acscatal.0c04474
Abstract: Nucleophilic addition of diborylalkyl reagents to N-alkyl or N-acylpyridinium and related heteroarenium salts has been developed as a key step for the synthesis of nonaromatic nitrogen heterocycles... read more here.
Keywords: heteroarenium; catalyzed regio; regio diastereoselective; heteroarenium salts ... See more keywords
d-Glucosamine as the Green Ligand for Cu(I)-Catalyzed Regio- and Stereoselective Domino Synthesis of (Z)-3-Methyleneisoindoline-1-ones and (E)-N-Aryl-4H-thiochromen-4-imines
Sign Up to like & getrecommendations! Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c03003
Abstract: d-Glucosamine, a natural, inexpensive, and conveniently accessible sugar, has been explored as an efficient ligand for the Cu(I)-catalyzed regio- and stereoselective synthesis of an array of (Z)-3-methyleneisoindoline-1-ones and (E)-N-aryl-4H-thiochromen-4-imines in good-to-excellent yield in a tandem… read more here.
Keywords: ligand catalyzed; catalyzed regio; reaction; regio stereoselective ... See more keywords