Bioorthogonal Metalloporphyrin‐Catalyzed Selective Methionine Alkylation in the Lanthipeptide Nisin
Sign Up to like & getrecommendations! Published in 2019 at "Chembiochem"
DOI: 10.1002/cbic.201800493
Abstract: Bioorthogonal catalytic modification of ribosomally synthesized and post‐translationally modified peptides (RiPPs) is a promising approach to obtaining novel antimicrobial peptides with improved properties and/or activities. Here, we present the serendipitous discovery of a selective and… read more here.
Keywords: metalloporphyrin catalyzed; bioorthogonal metalloporphyrin; catalyzed selective; lanthipeptide nisin ... See more keywords
Nucleophilic RhI Catalyzed Selective Isomerization of Terminal Aziridines to Enamides
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DOI: 10.1002/cctc.202000597
Abstract: The selective isomerization of various terminal N‐Boc protected aziridines to enamides was realized using the highly reactive nucleophilic rhodium catalyst C with the Lewis acid LiNTf2 as co‐catalyst under moderate conditions. The reaction proceeds smoothly… read more here.
Keywords: rhi catalyzed; nucleophilic rhi; catalyzed selective; aziridines enamides ... See more keywords
Ag-Catalyzed selective fluorination of 6-substituted 2-amionpyrazines
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2018.12.003
Abstract: Abstract The fluorination of 6-substituted 2-aminopyrazines with Selectfluor in the presence of Ag2CO3 is established under mild conditions. This method selectively produced the fluorinated 2-aminopyrazine derivatives in fair to high yield. The regioselectivity of this… read more here.
Keywords: fluorination substituted; substituted amionpyrazines; chemistry; fluorination ... See more keywords
Iron-catalyzed selective oxidative arylation of phenols and biphenols
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DOI: 10.1016/j.tet.2017.03.094
Abstract: Abstract The single-step synthesis of protected fucols and unnatural polyaryls by biomimetic oxidative cross-coupling between phenolic components and 1,3,5-trimethoxybenzene catalyzed by FeCl3 in fluorinated solvents is reported. The regioselectivity (ortho, meta or para) and the… read more here.
Keywords: oxidative arylation; catalyzed selective; arylation phenols; iron catalyzed ... See more keywords
Palladium-catalyzed selective ortho C–H alkoxylation at 4-aryl of 1, 4-disubstituted 1, 2, 3-triazoles
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DOI: 10.1016/j.tet.2020.130985
Abstract: Abstract The ortho- C–H bonds at C(4)-aryl of 1, 4-disubstituted 1, 2, 3-triazoles were regioselectively alkoxylated in good to excellent yields with under the directing of the triazole ring. Some products were found to exhibit… read more here.
Keywords: disubstituted triazoles; catalyzed selective; ortho alkoxylation; selective ortho ... See more keywords
Iron-catalyzed δ-selective conjugate addition of methyl and cyclopropyl Grignard reagents to α,β,γ,δ-unsaturated esters and amides
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DOI: 10.1016/j.tetlet.2018.12.043
Abstract: Abstract Iron-catalyzed δ-selective conjugate addition of methyl and cyclopropyl Grignard reagents to α,β,γ,δ-unsaturated esters and amides took place in good yields to give products exclusively with cis-β,γ-olefinic bond. read more here.
Keywords: iron catalyzed; conjugate addition; methyl cyclopropyl; selective conjugate ... See more keywords
Rh(I)-Catalyzed C6-Selective Decarbonylative Alkylation of 2-Pyridones with Alkyl Carboxylic Acids and Anhydrides.
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DOI: 10.1021/acs.orglett.0c01277
Abstract: A Rh-catalyzed chelation-assisted C6-selective C-H activation/alkylation of 2-pyridones with readily available alkyl carboxylic acids or anhydrides is introduced. The reaction proceeds via substrate decarbonylation. This approach merges C-H functionalization with readily available anhydrides, allowing for… read more here.
Keywords: alkyl carboxylic; catalyzed selective; carboxylic acids; alkylation pyridones ... See more keywords
Rhodium-Catalyzed Selective C(sp2)-H Activation/Annulation of tert-Butyl Benzoyloxycarbamates with 1,3-Diynes: A One Step Access to Alkynylated Isocoumarins and Bis-Isocoumarins.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01901
Abstract: We report here a Rh(III) catalyzed regio- and stereoselective synthesis of alkynylated and bis-isocoumarin from 1,3-dialkyne. Exclusive one-pot formation of 3,3-bis-isocoumarin isomers has been achieved by eliminating several other possibilities. This is the first example… read more here.
Keywords: bis isocoumarin; selective sp2; rhodium catalyzed; sp2 activation ... See more keywords
Gold(I)-Catalyzed Selective Hydroarylation of Indoles with Haloalkynes.
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DOI: 10.1021/acs.orglett.2c01921
Abstract: A highly regio- and stereoselective synthesis of a Z-alkenyl indole via the gold-catalyzed addition of an indole to a haloalkyne was developed. In the presence of gold catalyst SIPrAuCl and cocatalyst NaBARF, a broad range… read more here.
Keywords: hydroarylation; selective hydroarylation; indoles haloalkynes; hydroarylation indoles ... See more keywords
Iridium-Catalyzed Selective trans-Semihydrogenation of 1,3-Enynes with Ethanol: Access to (E,E)-1,4-Diarylbutadienes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02327
Abstract: A trans-semihydrogenation of 1,3-enynes with ethanol as the hydrogen source was developed using a new (PCN)Ir complex as the precatalyst and tBuNH2 as the cocatalyst. This catalyst system provides an efficient and atom-economical access to… read more here.
Keywords: enynes ethanol; semihydrogenation enynes; iridium catalyzed; trans semihydrogenation ... See more keywords
Iridium-Catalyzed Selective B(4)-H Amination of o-Carboranes with Anthranils.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02590
Abstract: We report here a catalytic selective cage B4-H amination of o-carboranes employing an Ir(III) complex as a catalyst and anthranils as aminating agents, leading to a large class of B4-aminated o-carboranes with very high yields… read more here.
Keywords: amination carboranes; iridium catalyzed; carboranes anthranils; amination ... See more keywords