Cascade reactions to 2,4-disubstituted thiazoles via ligand-free palladium(II)-catalyzed C(sp)–C(sp2) coupling
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DOI: 10.1016/j.tet.2020.130953
Abstract: Abstract A simple construction for various 2,4-disubstituted thiazoles via palladium(II)-catalyzed C(sp)–C(sp2) and C-N cascade coupling reactions was developed. Various substrates can be tolerated with good yields. And its ligand-free condition demonstrates the practicability of this… read more here.
Keywords: disubstituted thiazoles; ligand free; catalyzed sp2; palladium catalyzed ... See more keywords
Synthesis of Diverse γ-Lactams via Rh-Catalyzed C(sp2)-H Addition to Aliphatic Nitriles.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01867
Abstract: We herein report an unprecedented pathway to access γ-lactams using acetonitrile analogues as coupling partners without oxidants, ligands, and Lewis acids. The reaction undergoes Rh-catalyzed C(sp2)-H addition to carbon-bound nitriles with the aid of an… read more here.
Keywords: sp2 addition; lactams via; synthesis diverse; catalyzed sp2 ... See more keywords
Enantioselective Copper-Catalyzed sp2/sp3 Diborylation of 1-Chloro-1-Trifluoromethylalkenes
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DOI: 10.1021/acscentsci.2c00339
Abstract: Fluorine-containing organoboron compounds have emerged as novel building blocks in chemical synthesis; among them, fluorinated sp2/sp3 diborylated compounds are particularly appealing, since they might undergo chemoselective and diversified transformations of different C–B bonds with fluorinated… read more here.
Keywords: sp2 sp3; chloro trifluoromethylalkenes; enantioselective copper; catalyzed sp2 ... See more keywords
Chromium(III)-catalyzed C(sp2)-H Alkynylation, Allylation, and Naphthalenation of Secondary Amides with Trimethylaluminum as Base.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c00127
Abstract: Among base metals used for C-H activation reactions, chromium(III) is rather unexplored despite its natural abundance and low toxicity. We report herein chromium(III)-catalyzed C(sp2)-H functionalization of an ortho-position of aromatic and α,β-unsaturated secondary amides using… read more here.
Keywords: iii; catalyzed sp2; secondary amides; iii catalyzed ... See more keywords
Palladium-catalyzed C(sp2)–H aminoimidoylation of isocyano-containing arenes: synthesis of amino substituted N-heterocycles
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DOI: 10.1039/c7qo00368d
Abstract: An efficient access to amino substituted phenanthridine and isoquinoline derivatives, through palladium-catalyzed C(sp2)–H aminoimidoylation, has been developed. This process applies O-benzoyl hydroxylamines as oxidative amino sources to generate amino Pd(II) intermediates, followed by isocyanide insertion… read more here.
Keywords: amino; catalyzed sp2; palladium catalyzed; sp2 aminoimidoylation ... See more keywords
Cp*Ir(iii)- and Cp*Rh(iii)-catalyzed C(sp2)–H amination of arenes using thioethers as directing groups
Sign Up to like & getrecommendations! Published in 2021 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo01353f
Abstract: A mild and selective Cp*Ir(iii)- and Cp*Rh(iii)-catalyzed direct C(sp2)–H amination of arenes and three types of nitrene precursor reagents is reported, with the assistance of a thioether directing group. read more here.
Keywords: iii iii; sp2 amination; catalyzed sp2; iii catalyzed ... See more keywords
Rh(iii)-Catalyzed C(sp2)–H functionalization/cyclization cascade of N-carboxamide indole and iodonium reagents for access to indoloquinazolinone derivatives
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DOI: 10.1039/d1gc01820e
Abstract: The sustainable synthesis of indoloquinazolinone derivatives from N-methoxycarbamoyl indoles and iodonium ylide reagents in methanol is described. read more here.
Keywords: functionalization cyclization; catalyzed sp2; indoloquinazolinone derivatives; iii catalyzed ... See more keywords
An Efficient Copper-Catalyzed C(sp2)–S Formation Starting from Aryl Iodides and Tetramethylthiuram Monosulfide (TMTM)
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DOI: 10.1055/s-0040-1707899
Abstract: A new, efficient copper-catalyzed C(sp2)–S formation of phenyl dithiocarbamates starting from aryl iodides and tetramethylthiuram monosulfide (TMTM) was developed. The target compounds, phenyl dithiocarbamates with active sites, were synthesized smoothly in good to excellent yields.… read more here.
Keywords: catalyzed sp2; formation; starting aryl; sp2 formation ... See more keywords