Iron-Catalyzed C–H Sulfonylmethylation of Indoles in Water–PEG400
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DOI: 10.1055/s-0039-1690675
Abstract: An iron-catalyzed C–H sulfonylmethylation of indoles in water–PEG400 has been developed using p-toluenesulfonylmethyl isocyanide. This protocol enables direct regioselective construction of Csp2–Csp3 bond at the C3 position of indoles with a broad range of substrate… read more here.
Keywords: indoles water; iron catalyzed; sulfonylmethylation indoles; catalyzed sulfonylmethylation ... See more keywords
Iron-Catalyzed Sulfonylmethylation of Imidazo[1,2-α]pyridines with N,N-Dimethylacetamide and Sodium Sulfinates
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DOI: 10.3390/molecules29133196
Abstract: Functionalized imidazo[1,2-α]pyridines are important scaffolds in pharmaceuticals. Herein, we present an efficient 3-sulfonylmethylation protocol for imidazo[1,2-α]pyridines by sodium sulfinates in DMA and H2O (2:1) via an FeCl3-catalyzed three-component coupling reaction. Various sulfonylmethyl imidazo[1,2-α]pyridines were thus… read more here.
Keywords: catalyzed sulfonylmethylation; imidazo; iron catalyzed; sodium sulfinates ... See more keywords