AgSbF6‐Catalyzed Tandem Reaction of 2‐Alkynylanilines with Cyclic Enynones: Efficient access to 3‐Furo[3,2‐c]chromenylindoles and Related Scaffolds
Sign Up to like & getrecommendations! Published in 2018 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.201700511
Abstract: A simple, mild, catalytic and efficient method for the straightforward synthesis of an interesting class of a range of 2-aryl/alkyl-substituted-3-(2-aryl/alkyl-4H-furo[3,2-c]chromen-4-yl)-1H-indoles in good to high yields is reported for the first time. This atom-efficient method proceeds… read more here.
Keywords: reaction alkynylanilines; agsbf6 catalyzed; tandem reaction; catalyzed tandem ... See more keywords
Oleylamine-catalyzed Tandem Knoevenagel/Michael Addition of 1,3-Cyclohexanediones with Aromatic Aldehydes
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Research in Chinese Universities"
DOI: 10.1007/s40242-018-7320-1
Abstract: A convenient and efficient method was developed for the synthesis of 2,2′-(arylmethylene)bis(3-hydrox- ycyclohex-2-enone) derivatives via the oleylamine-catalyzed tandem Knoevenagel/Michael addition reactions of aromatic aldehydes and cyclohexane-1,3-diones. This transformation proceeded without any metal catalyst in non-toxic… read more here.
Keywords: michael addition; catalyzed tandem; oleylamine catalyzed; tandem knoevenagel ... See more keywords
Copper-catalyzed tandem cyclization and vinylation for the synthesis of 2-trifluoromethyl benzofurans
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DOI: 10.1016/j.jfluchem.2019.109418
Abstract: Abstract A copper-catalyzed tandem cyclization and vinylation of 2-chloro-1-(2-bromoaryl)-3,3,3-trifluoropropenes with KOH has been developed for the synthesis of 2-trifluoromethyl benzofuran derivatives. The reaction involves dual C O bonds formation and hydroarylation of aryl trifluoropropynes. This… read more here.
Keywords: tandem cyclization; cyclization vinylation; catalyzed tandem; synthesis trifluoromethyl ... See more keywords
Divergent Conversion of Double Isocyanides with Alkenyl Bromide to Polysubstituted Pyrroles and 4-Imino-4,5-dihydropyrrolo[3,4-b]pyrrol-6(1H)-one Derivatives by Pd-Catalyzed Tandem Cyclization Reactions.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04146
Abstract: Herein a novel and concise approach to pyrrole skeletons via Pd-catalyzed tandem cyclization reactions is investigated. The substrates for the transformation could be readily prepared by phosphoric acid-catalyzed Ugi reactions with available starting materials. In… read more here.
Keywords: catalyzed tandem; cyclization reactions; divergent conversion; tandem cyclization ... See more keywords
Directed Copper-Catalyzed Tandem Radical Cyclization Reaction of Alkyl Bromides and Unactivated Olefins.
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DOI: 10.1021/acs.orglett.2c00835
Abstract: The free radical cyclization reaction is a promising strategy for ring framework formation. Herein, we report a copper-catalyzed tandem radical cyclization strategy for preparing substituted lactam derivatives. This reaction proceeds through a radical coupling approach,… read more here.
Keywords: copper catalyzed; cyclization; radical cyclization; cyclization reaction ... See more keywords
Visible-Light-Catalyzed Tandem Radical Addition/1,5-Hydrogen Atom Transfer/Cyclization of 2-Alkynylarylethers with Sulfonyl Chlorides.
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DOI: 10.1021/acs.orglett.2c01977
Abstract: A novel visible-light-catalyzed tandem radical addition/1,5-hydrogen atom transfer/cyclization cascade of 2-alkynylarylethers with sulfonyl chlorides in 2-methyltetrahydrofuran was developed under photocatalyst- and additive-free conditions. This reaction relies on unique energy transfer and solvent-radical relay strategies to… read more here.
Keywords: catalyzed tandem; transfer; light catalyzed; tandem radical ... See more keywords
Gold(I)-Catalyzed Tandem Intramolecular Methoxylation/Double Aldol Condensation Strategy Yielding 2,2'-Spirobi[indene] Derivatives.
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DOI: 10.1021/acs.orglett.2c02653
Abstract: The syntheses of 2,2'-spirobi[indene] derivatives based on a gold(I)-catalyzed tandem strategy involving intramolecular methoxylation/double aldol condensation were achieved. Examination of the scope of this tandem reaction by using a batch of alkynone substrates disclosed that… read more here.
Keywords: catalyzed tandem; indene derivatives; spirobi indene; tandem ... See more keywords
Rhodium-Catalyzed Tandem C-H Annulation Enabled by Transient Directing Group Strategy and Sequential Nucleophilic Substitution.
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DOI: 10.1021/acs.orglett.2c02853
Abstract: A novel protocol of rhodium-catalyzed tandem C-H annulation of aldehyde and aniline with diazonaphthalen-1(2H)-one via transient directing group strategy and sequential nucleophilic substitution has been demonstrated in moderate to excellent yields. This reaction proceeds smoothly… read more here.
Keywords: nucleophilic substitution; catalyzed tandem; rhodium catalyzed; tandem annulation ... See more keywords
Ligand-Controlled Nickel-Catalyzed Tandem Isomerization/Regiodivergent Hydroheteroarylation of α-Alkenes with Heteroarenes.
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DOI: 10.1021/acs.orglett.2c03689
Abstract: We herein describe an accessible ligand-controlled nickel-catalyzed tandem isomerization/regiodivergent hydroheteroarylation of α-alkenes with a series of heteroarenes, wherein the NHC ligand of heteroleptic Ni(II) complexes of the type Ni(NHC)[P(OEt)3]Br2 displayed significant effects on regulation. In… read more here.
Keywords: catalyzed tandem; controlled nickel; nickel catalyzed; isomerization ... See more keywords
Phosphine-Catalyzed Tandem Annulation of Allenylic Alcohols with 1,1-Dicyanoalkenes.
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DOI: 10.1021/acs.orglett.3c01066
Abstract: The phosphine-catalyzed tandem annulation of allenylic alcohols with 1,1-dicyanoalkenes has been developed, giving various bicyclic tetrahydrocyclopentafuran derivatives in 40-89% yields with moderate to excellent diastereoselectivities. The fused ring was furnished through a sequential (3 +… read more here.
Keywords: catalyzed tandem; annulation; allenylic alcohols; phosphine catalyzed ... See more keywords
Copper-Catalyzed Tandem Cross-Coupling/[2 + 2] Cycloaddition of 1,6-Allenynes with Diazo Compounds to 3-Azabicyclo[5.2.0] Ring Systems.
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DOI: 10.1021/acs.orglett.9b03727
Abstract: An unprecedented copper-catalyzed tandem cross-coupling/[2 + 2] cycloaddition of 1,6-allenynes with diazo compounds was reported, chemo- and regioselectively providing 3-azabicyclo[5.2.0] frameworks in moderate to excellent yields under mild reaction conditions. Moreover, the products readily convert… read more here.
Keywords: tandem cross; coupling cycloaddition; copper catalyzed; catalyzed tandem ... See more keywords