Multicomponent reaction for the synthesis of highly functionalized piperidine scaffolds catalyzed by TMSI
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DOI: 10.1007/s11164-020-04208-6
Abstract: An efficient method for the synthesis of highly functionalized piperidines via one-pot domino reaction of β-ketoesters, aromatic aldehydes, and aromatic amines was reported. This multicomponent coupling was catalyzed by TMSI in methanol at room temperature,… read more here.
Keywords: synthesis highly; highly functionalized; multicomponent reaction; catalyzed tmsi ... See more keywords