Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-39374-0
Abstract: Moraxella catarrhalis is a host-adapted bacterial pathogen that causes otitis media and exacerbations of chronic obstructive pulmonary disease. This study characterises the conserved M. catarrhalis extracellular nuclease, a member of the ββα metal finger family… read more here.
Keywords: catarrhalis nucm; catarrhalis; moraxella catarrhalis; entry nuclease ... See more keywords
An integrated complete-genome sequencing and systems biology approach to predict antimicrobial resistance genes in the virulent bacterial strains of Moraxella catarrhalis.
Sign Up to like & getrecommendations! Published in 2023 at "Briefings in functional genomics"
DOI: 10.1093/bfgp/elad005
Abstract: Moraxella catarrhalis is a symbiotic as well as mucosal infection-causing bacterium unique to humans. Currently, it is considered as one of the leading factors of acute middle ear infection in children. As M. catarrhalis is… read more here.
Keywords: bacterial strains; catarrhalis; moraxella catarrhalis; antimicrobial resistance ... See more keywords
The characterization of Moraxella catarrhalis carried in the general population
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000820
Abstract: Moraxella catarrhalis is a common cause of respiratory tract infection, particularly otitis media in children, whilst it is also associated with the onset of exacerbation in chronic obstructive pulmonary disease in adults. Despite the need… read more here.
Keywords: prevalence; catarrhalis; catarrhalis carried; moraxella catarrhalis ... See more keywords
Virulence determinants of Moraxella catarrhalis: distribution and considerations for vaccine development.
Sign Up to like & getrecommendations! Published in 2017 at "Microbiology"
DOI: 10.1099/mic.0.000523
Abstract: Moraxella catarrhalis is a human-restricted opportunistic bacterial pathogen of the respiratory mucosa. It frequently colonizes the nasopharynx asymptomatically, but is also an important causative agent of otitis media (OM) in children, and plays a significant… read more here.
Keywords: virulence; virulence factors; catarrhalis; moraxella catarrhalis ... See more keywords
Rothia from the Human Nose Inhibit Moraxella catarrhalis Colonization with a Secreted Peptidoglycan Endopeptidase
Sign Up to like & getrecommendations! Published in 2023 at "mBio"
DOI: 10.1128/mbio.00464-23
Abstract: Moraxella catarrhalis is a pathobiont of the respiratory tract, responsible for ear infections in children and wheezing illnesses in children and adults with chronic respiratory diseases. Detection of M. catarrhalis during wheezing episodes in early… read more here.
Keywords: rothia; catarrhalis; moraxella catarrhalis; respiratory ... See more keywords
Hockey puck sign: identifying Moraxella catarrhalis
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-243677
Abstract: © BMJ Publishing Group Limited 2021. No commercial reuse. See rights and permissions. Published by BMJ. DESCRIPTION A 76yearold male patient with diabetes mellitus presented with a 4day history of productive cough and fever. He… read more here.
Keywords: catarrhalis; puck sign; moraxella catarrhalis; hockey puck ... See more keywords
Differential responses of COPD macrophages to respiratory bacterial pathogens
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DOI: 10.1183/23120541.00044-2022
Abstract: COPD patients have increased susceptibility to airway bacterial colonisation. Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae are three of the most common respiratory bacterial species in COPD. H. influenzae colonisation, but not other bacteria, in… read more here.
Keywords: respiratory bacterial; influenzae catarrhalis; apoptosis; pneumoniae ... See more keywords
Aptasensor for the Detection of Moraxella catarrhalis Adhesin UspA2
Sign Up to like & getrecommendations! Published in 2023 at "Bioengineering"
DOI: 10.3390/bioengineering10020178
Abstract: Innovative point-of-care (PoC) diagnostic platforms are desirable to surpass the deficiencies of conventional laboratory diagnostic methods for bacterial infections and to tackle the growing antimicrobial resistance crisis. In this study, a workflow was implemented, comprising… read more here.
Keywords: aptasensor; catarrhalis; detection; moraxella catarrhalis ... See more keywords
Genotypic and Phenotypic Characteristics of Moraxella catarrhalis from Patients and Healthy Asymptomatic Participants among Preschool Children
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11090984
Abstract: (1)Background: M. catarrhalis can ascend into the middle ear, where it is a prevalent causative agent of otitis media in children, or enter the lower respiratory tract, where it is associated with community-acquired pneumonia (CAP).… read more here.
Keywords: preschool children; healthy asymptomatic; catarrhalis; asymptomatic participants ... See more keywords