Replication Catastrophe: When a Checkpoint Fails because of Exhaustion.
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DOI: 10.1016/j.molcel.2017.05.001
Abstract: Proliferating cells rely on the so-called DNA replication checkpoint to ensure orderly completion of genome duplication, and its malfunction may lead to catastrophic genome disruption, including unscheduled firing of replication origins, stalling and collapse of… read more here.
Keywords: replication catastrophe; replication checkpoint; checkpoint; catastrophe checkpoint ... See more keywords