HIV Infection Induces Extracellular Cathepsin B Uptake and Damage to Neurons
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DOI: 10.1038/s41598-019-44463-1
Abstract: HIV-associated neurocognitive disorders prevail in 20–50 percent of infected individuals. Macrophages transmigrate through the blood brain barrier during HIV-1 infection, triggering neuronal dysfunction. HIV-infected macrophages secrete cathepsin B (CATB), and serum amyloid p component (SAPC),… read more here.
Keywords: hiv infection; catb; dysfunction; catb sapc ... See more keywords