The Catecholaldehyde Hypothesis for the Pathogenesis of Catecholaminergic Neurodegeneration: What We Know and What We Do Not Know
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DOI: 10.3390/ijms22115999
Abstract: 3,4-Dihydroxyphenylacetaldehyde (DOPAL) is the focus of the catecholaldehyde hypothesis for the pathogenesis of Parkinson’s disease and other Lewy body diseases. The catecholaldehyde is produced via oxidative deamination catalyzed by monoamine oxidase (MAO) acting on cytoplasmic… read more here.
Keywords: catecholaldehyde hypothesis; catecholaminergic neurodegeneration; hypothesis; hypothesis pathogenesis ... See more keywords