Electrical storms induced by multiple shocks in catecholaminergic polymorphic ventricular tachycardia, spotlight
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.13122
Abstract: An electrical storm ensued following multiple shocks by an implantable cardioverter defibrillator (ICD). The prevention of such electrical storms is prognostically important and includes revision of medical therapy, modification of ICD settings, cardiac sympathectomy, and… read more here.
Keywords: induced multiple; storms induced; electrical storms; shocks catecholaminergic ... See more keywords
A 35-year effective treatment of catecholaminergic polymorphic ventricular tachycardia with propafenone
Sign Up to like & getrecommendations! Published in 2019 at "HeartRhythm Case Reports"
DOI: 10.1016/j.hrcr.2018.04.003
Abstract: Key Teaching Points • Despite proven catecholaminergic polymorphic ventricular tachycardia (CPVT) with pathogen RyR2 mutation and recurrent syncope, patients could have a favorable long-term outcome over 35 years under treatment. • Propafenone could be effective… read more here.
Keywords: ventricular tachycardia; effective treatment; polymorphic ventricular; treatment ... See more keywords
Scared to death—A novel mutation in catecholaminergic polymorphic ventricular tachycardia
Sign Up to like & getrecommendations! Published in 2020 at "HeartRhythm Case Reports"
DOI: 10.1016/j.hrcr.2020.01.009
Abstract: The decision to implant an implantable cardioverter-defibrillator in patients with CPVT is challenging, as there are no randomized controlled Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare familial cardiac arrhythmia that results in bidirectional… read more here.
Keywords: death; ventricular tachycardia; polymorphic ventricular; catecholaminergic polymorphic ... See more keywords
Sudden death after inappropriate shocks of implantable cardioverter defibrillator in a catecholaminergic polymorphic ventricular tachycardia case with a novel RyR2 mutation.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of electrocardiology"
DOI: 10.1016/j.jelectrocard.2021.09.015
Abstract: BACKGROUND Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmogenic syndrome and a cause of exercise-related sudden death. CPVT has been reported to be caused by gain of function underlying a mutation of cardiac ryanodine… read more here.
Keywords: sudden death; ryr2 mutation; ryr2; catecholaminergic polymorphic ... See more keywords
Documenting the descent – remote monitoring and adult-onset Catecholaminergic Polymorphic Ventricular Tachycardia associated with ventricular fibrillation and bradycardia
Sign Up to like & getrecommendations! Published in 2021 at "Cardiology in the Young"
DOI: 10.1017/s1047951121002377
Abstract: Abstract This image highlights a 38-year-old female with ventricular fibrillation and spontaneous return to sinus rhythm found on an implantable loop recorder inserted for recurrent syncope. Ultimately, she was diagnosed with catecholaminergic polymorphic ventricular tachycardia,… read more here.
Keywords: ventricular tachycardia; polymorphic ventricular; catecholaminergic polymorphic; ventricular fibrillation ... See more keywords
Ventricular hyperinnervation in a mouse model of catecholaminergic polymorphic ventricular tachycardia
Sign Up to like & getrecommendations! Published in 2024 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvae088.098
Abstract: Type of funding sources: Foundation. Main funding source(s): European Society of Cardiology Basic Research Fellowship. Dutch Heart Foundation Dekker Grant Inherited arrhythmia syndromes are a leading cause of sudden cardiac death in young and otherwise… read more here.
Keywords: ryr2; cpvt; mouse model; catecholaminergic polymorphic ... See more keywords
Catecholaminergic Polymorphic Ventricular Tachycardia.
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric emergency care"
DOI: 10.1097/01.pec.0000520710.58614.76
Abstract: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a condition characterized by an abnormal heart rhythm (arrhythmia). As the heart rate increases in response to physical activity or emotional stress, it can trigger an abnormally fast and… read more here.
Keywords: polymorphic ventricular; catecholaminergic polymorphic; ventricular tachycardia; tachycardia ... See more keywords
Unusual catecholaminergic polymorphic ventricular tachycardia and bradycardia caused by a novel triadin variant in 2 siblings from a Malian family
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DOI: 10.1097/md.0000000000043596
Abstract: Rationale: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a hereditary arrhythmia syndrome that can cause sudden cardiac death, particularly in young individuals. CPVT is often linked to triadin (TRDN) variants that disrupt calcium regulation in the… read more here.
Keywords: polymorphic ventricular; family; ventricular tachycardia; catecholaminergic polymorphic ... See more keywords
A gain of function ryanodine receptor 2 mutation (R1760W‐RyR2) in catecholaminergic polymorphic ventricular tachycardia
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13722
Abstract: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome associated with Ca2+ leak predominantly caused by ryanodine receptor 2 (RyR2) mutations. We identified a R1760W‐RyR2 mutation located between the N‐terminal domain and the central… read more here.
Keywords: polymorphic ventricular; catecholaminergic polymorphic; r1760w ryr2; ryr2 ... See more keywords
Efficacy of RyR2 inhibitor EL20 in induced pluripotent stem cell‐derived cardiomyocytes from a patient with catecholaminergic polymorphic ventricular tachycardia
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16521
Abstract: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited cardiac arrhythmia syndrome that often leads to sudden cardiac death. The most common form of CPVT is caused by autosomal‐dominant variants in the cardiac ryanodine receptor type‐2… read more here.
Keywords: el20; ventricular tachycardia; polymorphic ventricular; ryr2 ... See more keywords
Nationwide experience of catecholaminergic polymorphic ventricular tachycardia caused by RyR2 mutations
Sign Up to like & getrecommendations! Published in 2017 at "Heart"
DOI: 10.1136/heartjnl-2016-310509
Abstract: Objective The aim of this study was to characterise disease penetrance, course of disease and use of antiarrhythmic medication and implantable cardioverter-defibrillator (ICD) therapy in a Danish nationwide cohort of patients with catecholaminergic polymorphic ventricular… read more here.
Keywords: nationwide experience; ventricular tachycardia; polymorphic ventricular; disease ... See more keywords