Synthesis, Purification, and Selective β2-AR Agonist and Bronchodilatory Effects of Catecholic Tetrahydroisoquinolines from Portulaca oleracea.
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DOI: 10.1021/acs.jnatprod.9b00418
Abstract: A green, biomimetic, phosphate-mediated Pictet-Spengler reaction was used in the synthesis of three catecholic tetrahydroisoquinolines, 1, 2, and 12, present in the medicinal plant Portulaca oleracea, as well as their analogues 3-11, 13, and 14,… read more here.
Keywords: agonist; catecholic tetrahydroisoquinolines; portulaca oleracea; synthesis purification ... See more keywords