Divergent roles of p120‐catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen‐induced rat skin tumors
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DOI: 10.1002/mc.22630
Abstract: The heterocyclic amine 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) targets multiple organs for tumorigenesis in the rat, including the colon and the skin. PhIP‐induced skin tumors were subjected to mutation screening, which identified genetic changes in Hras (7/40, 17.5%)… read more here.
Keywords: catenin; skin tumors; p120 catenin; catenin isoforms ... See more keywords