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   Articles with "catenin myc" as a keyword



Activation of nuclear β-catenin/c-Myc axis promotes oxidative stress injury in streptozotocin-induced diabetic cardiomyopathy.

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recommendations! Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.10.027

Abstract: Myocardial oxidative stress injury plays a crucial role in the pathogenesis of diabetic cardiomyopathy (DCM). Wnt/β-catenin signaling has been reported to involve in various heart diseases. However, the underlying mechanism associated with β-catenin in DCM… read more here.

Keywords: nuclear catenin; catenin myc; catenin; oxidative stress ... See more keywords
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A feedback circuit comprising EHD1 and 14-3-3ζ sustains β-catenin/c-Myc-mediated aerobic glycolysis and proliferation in non-small cell lung cancer.

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recommendations! Published in 2021 at "Cancer letters"

DOI: 10.1016/j.canlet.2021.06.023

Abstract: Mammalian Eps15 homology domain 1 (EHD1) participates in the development of non-small cell lung cancer (NSCLC). However, its role in mediating aerobic glycolysis remains unclear. Herein, microarray analysis revealed that EHD1 expression was significantly correlated… read more here.

Keywords: catenin myc; glycolysis; aerobic glycolysis; circuit ... See more keywords

HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1

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recommendations! Published in 2019 at "Cancers"

DOI: 10.3390/cancers11101436

Abstract: Therapy of acute myeloid leukemia (AML) is unsatisfactory. Histone deacetylase inhibitors (HDACi) are active against leukemic cells in vitro and in vivo. Clinical data suggest further testing of such epigenetic drugs and to identify mechanisms… read more here.

Keywords: catenin myc; wt1; myc wt1; hdac3 ... See more keywords

Complement factor I knockdown inhibits colon cancer development by affecting Wnt/β-catenin/c-Myc signaling pathway and glycolysis

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recommendations! Published in 2024 at "World Journal of Gastrointestinal Oncology"

DOI: 10.4251/wjgo.v16.i6.2646

Abstract: BACKGROUND Colon cancer (CC) occurrence and progression are considerably influenced by the tumor microenvironment. However, the exact underlying regulatory mechanisms remain unclear. AIM To investigate immune infiltration-related differentially expressed genes (DEGs) in CC and specifically… read more here.

Keywords: catenin myc; cfi; wnt catenin; complement factor ... See more keywords

TMEM105 modulates disulfidptosis and tumor growth in pancreatic cancer via the β-catenin-c-MYC-GLUT1 axis

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recommendations! Published in 2025 at "International Journal of Biological Sciences"

DOI: 10.7150/ijbs.104598

Abstract: Background: Pancreatic cancer (PCa) is one of the most malignant diseases in the world. Different from ferroptosis and apoptosis, disulfidptosis is a novel type of cell death. The role of disulfidptosis in PCa remains uncovered.… read more here.

Keywords: catenin myc; pca; tmem105; disulfidptosis ... See more keywords