Cancer driver G-protein coupled receptor (GPCR) induced β-catenin nuclear localization: the transcriptional junction
Sign Up to like & getrecommendations! Published in 2017 at "Cancer and Metastasis Reviews"
DOI: 10.1007/s10555-017-9711-z
Abstract: G protein-coupled receptors (GPCRs) comprise the main signal-transmitting components in the cell membrane. Over the past several years, biochemical and structural analyses have immensely enhanced our knowledge of GPCR involvement in health and disease states.… read more here.
Keywords: nuclear localization; protein coupled; catenin nuclear; localization transcriptional ... See more keywords
β-catenin nuclear translocation induced by HIF-1α overexpression leads to the radioresistance of prostate cancer
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Oncology"
DOI: 10.3892/ijo.2018.4368
Abstract: Hypoxia-inducible factor-1α (HIF-1α) is known to play crucial roles in tumor radioresistance; however, the molecular mechanisms responsible for the promotion of tumor radioresistance by HIF-1α remain unclear. β-catenin is known to be involved in the… read more here.
Keywords: catenin; catenin nuclear; cell; nuclear translocation ... See more keywords