Inhibition of MDFI attenuates proliferation and glycolysis of Helicobacter pylori‐infected gastric cancer cells by inhibiting Wnt/β‐catenin pathway
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DOI: 10.1002/cbin.11907
Abstract: MyoD family inhibitor (MDFI) is a myogenic transcription factor regulatory protein. MDFI has been proven to be upregulated and to promote cell proliferation in colorectal cancer. However, the role of MDFI in gastric cancer (GC)… read more here.
Keywords: cell; proliferation glycolysis; wnt catenin; mdfi ... See more keywords
CircRNF121 knockdown suppresses the progression of cervical cancer by regulating miR‐153‐3p/ATF2 axis and wnt/β‐catenin pathway
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DOI: 10.1002/ddr.21908
Abstract: Cervical cancer (CC) is a common malignancy in gynecology. Emerging evidence has demonstrated that circular RNAs (circRNAs) act as vital mediators in CC. However, the roles of circRNA ring finger protein 121 (circRNF121) in CC… read more here.
Keywords: cervical cancer; mir 153; wnt catenin; 153 atf2 ... See more keywords
Histone deacetylase 10 exerts antitumor effects on cervical cancer via a novel microRNA‐223/TXNIP/Wnt/β‐catenin pathway
Sign Up to like & getrecommendations! Published in 2021 at "IUBMB Life"
DOI: 10.1002/iub.2450
Abstract: Dysfunction of histone deacetylase 10 (HDAC10) has been suggested in the carcinogenesis of cervical cancer (CC). However, its association with microRNAs (miRNAs) in CC remains exclusive. Hence, this study aims to probe the role of… read more here.
Keywords: cervical cancer; histone deacetylase; catenin pathway; txnip ... See more keywords
Inhibition of MAC30 exerts antitumor effects in nasopharyngeal carcinoma via affecting the Akt/GSK‐3β/β‐catenin pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23061
Abstract: Meningioma‐associated protein 30 (MAC30) is a vital modulator of malignant transformation in numerous cancers. Yet, the involvement of MAC30 in nasopharyngeal carcinoma (NPC) is undetermined. This study was devoted to the study of the function… read more here.
Keywords: inhibition; mac30; via affecting; catenin ... See more keywords
Andrographolide suppresses breast cancer progression by modulating tumor‐associated macrophage polarization through the Wnt/β‐catenin pathway
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DOI: 10.1002/ptr.7578
Abstract: Andrographolide(ADE) has been demonstrated to inhibit tumor growth through direct cytotoxicity on tumor cells. However, its potential activity on tumor microenvironment (TME) remains unclear. Tumor‐associated macrophages (TAMs), composed mainly of M2 macrophages, are the key… read more here.
Keywords: macrophage polarization; tumor associated; polarization; tumor ... See more keywords
Berberine plays a cardioprotective role by inhibiting macrophage Wnt5a/β‐catenin pathway in the myocardium of mice after myocardial infarction
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DOI: 10.1002/ptr.7592
Abstract: Myocardial infarction (MI) is one of the diseases with high fatality rate. Berberine (BBR) is a monomer compound with various biological functions. And some studies have confirmed that BBR plays an important role in alleviating… read more here.
Keywords: wnt5a catenin; myocardial infarction; berberine; catenin pathway ... See more keywords
Inhibition of FAM83D displays antitumor effects in glioblastoma via down‐regulation of the AKT/Wnt/β‐catenin pathway
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23488
Abstract: Up‐regulation of family with sequence similarity 83 member D (FAM83D) has been acknowledged as a vital contributor for the carcinogenesis of numerous cancers. The relevance of FAM83D in glioblastoma (GBM), however, is not well understood.… read more here.
Keywords: wnt catenin; catenin; catenin pathway; antitumor effects ... See more keywords
KIF3A regulates the Wnt/β-catenin pathway via transporting β-catenin during spermatogenesis in Eriocheir sinensis
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DOI: 10.1007/s00441-020-03220-x
Abstract: The Wnt/β-catenin pathway participates in many important physiological events such as cell proliferation and differentiation in the male reproductive system. We found that Kinesin-2 motor KIF3A is highly expressed during spermatogenesis in Eriocheir sinensis; it… read more here.
Keywords: spermatogenesis; catenin; catenin pathway; kif3a ... See more keywords
Hydrogen Sulfide Attenuates High Glucose-induced Myocardial Injury in Rat Cardiomyocytes by Suppressing Wnt/beta-catenin Pathway
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DOI: 10.1007/s11596-019-2120-5
Abstract: Diabetic cardiomyopathy (DCM) is one of the major heart complications of diabetic patients. Hydrogen sulfide (H2S) is now recognized as an important signaling molecule and has been shown to attenuate the development of diabetic cardiomyopathy.… read more here.
Keywords: high glucose; catenin pathway; rat cardiomyocytes; glucose induced ... See more keywords
Diwu Yanggan Modulates the Wnt/β-catenin Pathway and Inhibits Liver Carcinogenesis Signaling in 2-AAF/PH Model Rats
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DOI: 10.1007/s11596-019-2123-2
Abstract: The activation of the Wnt/β-catenin signaling pathway in oval cells after liver injury is implicated in hepatocarcinogenesis. Diwu Yanggan capsule is a Chinese herbal medicine that has been used for treating liver disorder. The present… read more here.
Keywords: diwu yanggan; catenin pathway; wnt catenin;
Aerobic Glycolysis Hypothesis Through WNT/Beta-Catenin Pathway in Exudative Age-Related Macular Degeneration
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DOI: 10.1007/s12031-017-0947-4
Abstract: Exudative age-related macular degeneration (AMD) is characterized by molecular mechanisms responsible for the initiation of choroidal neovascularization (CNV). Inflammatory processes are associated with upregulation of the canonical WNT/beta-catenin pathway in exudative AMD. We focus this… read more here.
Keywords: beta catenin; wnt beta; catenin pathway; aerobic glycolysis ... See more keywords