Articles with "catenin selectively" as a keyword



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Allosteric inhibitor of β-catenin selectively targets oncogenic Wnt signaling in colon cancer

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-60784-y

Abstract: Abnormal regulation of β-catenin initiates an oncogenic program that serves as a main driver of many cancers. Albeit challenging, β-catenin is an attractive drug target due to its role in maintenance of cancer stem cells… read more here.

Keywords: allosteric inhibitor; inhibitor catenin; catenin; cancer ... See more keywords