Silencing of Glut1 induces chemoresistance via modulation of Akt/GSK-3β/β-catenin/survivin signaling pathway in breast cancer cells.
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DOI: 10.1016/j.abb.2017.08.009
Abstract: Cancer cells require increased aerobic glycolysis to support rapid cell proliferation. For their increased energy demands, cancer cells express glucose transporter (Glut) proteins at a high level. Glut1 is associated with basal-like breast cancer and… read more here.
Keywords: catenin survivin; akt gsk; breast cancer; glut1 ... See more keywords