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Published in 2017 at "Journal of Peptide Science"
DOI: 10.1002/psc.3014
Abstract: Cathepsin D (Cath D) is overexpressed and secreted in a number of solid tumors and involved in the progress of tumor invasion, proliferation, metastasis, and apoptosis. Inhibition of Cath D is regarded as an attractive…
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Keywords:
cyanobacterial peptides;
cathepsin;
cath;
peptides prototype ... See more keywords
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Published in 2018 at "Journal of Peptide Science"
DOI: 10.1002/psc.3089
Abstract: Cathelicidins are an important family of antimicrobial peptide effectors of innate immunity in vertebrates. Two members of this group, CATH‐1 and CATH‐2, have been identified and characterized in teleosts (ray‐finned fish). In this study, we…
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Keywords:
cath;
induced expression;
expression;
expression cathelicidins ... See more keywords
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Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12078
Abstract: Abstract Right ventricular (RV) function critically affects the outcomes of patients with pulmonary hypertension (PH). Pressure wave analysis using Swan‒Ganz catheterization (SG‐cath) allows for the calculation of indices of RV function. However, the accuracy of…
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Keywords:
micromanometry derived;
cath;
pressure;
right ventricular ... See more keywords
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Published in 2022 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2022.104377
Abstract: Cathelicidins have antimicrobial and immunomodulatory activities. Previous studies have shown that chicken cathelicidin-2 (CATH-2) exerts strong anti-inflammatory activity through LPS neutralization. However, it is still unclear whether other intracellular signaling pathways are involved in CATH-2…
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Keywords:
nlrp3 inflammasome;
lps primed;
secretion;
activity ... See more keywords
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Published in 2021 at "Journal of Heart and Lung Transplantation"
DOI: 10.1016/j.healun.2021.01.992
Abstract: Purpose The purpose of this study is to investigate whether performing cardiac catheterization (cath) in pediatric lung transplantation (LTx) candidates without a diagnosis of pulmonary hypertension (PHTN) impacts listing outcomes. Methods The UNOS Registry was…
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Keywords:
diagnosis;
cath;
without diagnosis;
pediatric lung ... See more keywords
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Published in 2024 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.4c00342
Abstract: Although bactericidal cationic antimicrobial peptides (AMPs) have been well characterized, less information is available about the antibacterial properties and mechanisms of action of nonbactericidal AMPs, especially nonbactericidal anionic AMPs. Herein, a novel anionic antimicrobial peptide…
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Keywords:
antimicrobial peptide;
nonbactericidal anionic;
peptide provides;
anionic antimicrobial ... See more keywords
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Published in 2022 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.2c00260
Abstract: As antimicrobial resistance poses an increasing threat to public health, it is urgent to develop new antimicrobial agents. In this paper, we identify a novel 30-residue peptide (Nv-CATH, NCNFLCKVKQRLRSVSSTSHIGMAIPRPRG) from the skin of the frog…
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Keywords:
antimicrobial immunomodulatory;
staphylococcus aureus;
cath;
mice ... See more keywords
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Published in 2025 at "ACS Omega"
DOI: 10.1021/acsomega.5c05443
Abstract: In light of the increasing prevalence of carbapenem-resistant Klebsiella pneumoniae (CRKP), which represents a significant public health threat, it is imperative to investigate novel therapeutic strategies. This study aims to assess the efficacy of the…
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Keywords:
klebsiella pneumoniae;
resistant klebsiella;
carbapenem;
cath ... See more keywords
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Published in 2020 at "Stroke"
DOI: 10.1161/str.51.suppl_1.tmp67
Abstract: Background: Current guidelines indicate reduced time to reperfusion with thrombectomy is strongly associated with better outcomes. Validated screening tools for large vessel occlusions are available for the prehospital setting. Objective: To reduce door to access…
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Keywords:
cath;
cath lab;
large vessel;
stat positive ... See more keywords
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Published in 2024 at "Veterinary Research"
DOI: 10.1186/s13567-024-01402-x
Abstract: Mastitis, often caused by bacterial infection, is an inflammatory condition affecting the mammary glands. The condition is particularly prevalent in dairy cattle. Current treatment of bovine mastitis heavily relies on the use of antibiotics. To…
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Keywords:
bovine mastitis;
mastitis;
mastitis causative;
cath ... See more keywords
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Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00454
Abstract: CATH-2TP5 is a linear cationic hybrid peptide, consequent from naturally occurring antimicrobial peptide (AMPs) Cathelicidin-2 (CATH-2) and Immunomodulatory peptide Thymopentin (TP5) having dynamic and potent anti-inflammatory activities without hemolytic effect. The biocompatible mechanism of CATH-2TP5…
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Keywords:
peptide cath;
cath 2tp5;
vitro impact;
cath ... See more keywords