Engineering the Biosynthesis of Late-Stage Vinblastine Precursors Precondylocarpine Acetate, Catharanthine, Tabersonine in Nicotiana benthamiana
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DOI: 10.1021/acssynbio.2c00434
Abstract: Vinblastine is a chemotherapy agent produced by the plant Catharanthus roseus in small quantities. Currently, vinblastine is sourced by isolation or semisynthesis. Nicotiana benthamiana is a plant heterologous host that can be used for reconstitution… read more here.
Keywords: vinblastine; precondylocarpine acetate; late stage; catharanthine tabersonine ... See more keywords