The role of the Golden2-like (GLK) transcription factor in regulating terpenoid indole alkaloid biosynthesis in Catharanthus roseus
Sign Up to like & getrecommendations! Published in 2024 at "Plant Cell Reports"
DOI: 10.1007/s00299-024-03208-9
Abstract: A GLK homologue was identified and functionally characterized in Catharanthus roseus. Silencing CrGLK with VIGS or the chloroplast retrograde signaling inducer lincomycin increased terpenoid indole alkaloid biosynthesis. Catharanthus roseus is the sole source of the… read more here.
Keywords: biosynthesis; roseus; tia biosynthesis; terpenoid indole ... See more keywords
Morphological Properties of Catharanthus roseus L. Seedlings Affected by Priming Techniques Under Natural Salinity Stress
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Plant Growth Regulation"
DOI: 10.1007/s00344-020-10118-z
Abstract: Catharanthus roseus is a great medicinal plant used for treating diseases such as cancer, as it contains different biochemicals including terpenoids. Salinity is a major stress, significantly decreasing the growth and yield of medicinal plants,… read more here.
Keywords: salinity stress; catharanthus roseus; stress; salinity ... See more keywords
Phytochemical, antioxidant, anti-proliferative and antimicrobial properties of Catharanthus roseus root extract, saponin-enriched and aqueous fractions
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-04786-8
Abstract: Catharanthus roseus (L.) G. Don (C. roseus) is a well-known medicinal plant for its source of alkaloids solely found in the leaves. Other parts including the root are usually discarded after the alkaloid extraction. This… read more here.
Keywords: catharanthus roseus; root extract; saponin enriched; enriched aqueous ... See more keywords
Efficient regeneration and improved sonication-assisted Agrobacterium transformation (SAAT) method for Catharanthus roseus
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DOI: 10.1007/s13205-016-0593-5
Abstract: Catharanthus roseus is an important medicinal plant known for its pharmacological qualities such as antimicrobial, anticancerous, antifeedant, antisterility, antidiabetic activities. More than 130 bioactive compounds like vinblastine, vindoline and vincristine have been synthesized in this… read more here.
Keywords: saat method; catharanthus roseus; regeneration; transformation ... See more keywords
A rich source of potential bioactive compounds with anticancer activities by Catharanthus roseus cambium meristematic stem cell cultures.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2018.02.021
Abstract: ETHNOPHARMACOLOGICAL IMPORTANCE Catharanthus roseus (L.) G. Don. is an important medicinal plant with rich sources of remarkable health benefits consisting more than 100 alkaloids and significant amounts of bioactive compounds, which have been widely used… read more here.
Keywords: anticancer activities; cambium meristematic; catharanthus roseus; bioactive compounds ... See more keywords
Effects of fungal extracts on vinblastine and vincristine production and their biosynthesis pathway genes in Catharanthus roseus
Sign Up to like & getrecommendations! Published in 2018 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2018.08.015
Abstract: Abstract Catharanthus roseus is an important medicinal plant due to the production of valuable anticancer secondary metabolites including vinblastine and vincristine. Due to the importance of these alkaloids and their small amounts in C. roseus,… read more here.
Keywords: vinblastine vincristine; production; catharanthus roseus; fungal extracts ... See more keywords
Phenotypic, genetic and expression profiling of a vindoline-rich genotype of Catharanthus roseus
Sign Up to like & getrecommendations! Published in 2021 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2021.02.004
Abstract: Abstract Catharanthus roseus is known for its scarce and expensive anticancer bisindole alkaloids, vincristine and vinblastine, which are derived from the coupling of monomeric terpenoid indole alkaloids, catharanthine and vindoline. Vindoline represents the bottleneck in… read more here.
Keywords: expression; vindoline; rich genotype; vindoline rich ... See more keywords
Metabolomics Analysis Reveals that Ethylene and Methyl Jasmonate Regulate Different Branch Pathways to Promote the Accumulation of Terpenoid Indole Alkaloids in Catharanthus roseus.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.7b00782
Abstract: The medicinal plant Catharanthus roseus accumulates large numbers of terpenoid indole alkaloids (TIAs), including the pharmaceutically important vinblastine, vincristine, ajmalicine, and serpentine. The phytohormone ethylene or methyl jasmonate (MeJA) can markedly enhance alkaloid accumulation. The… read more here.
Keywords: catharanthus roseus; analysis; tia biosynthesis; roseus ... See more keywords
Mechanistic and kinetic modeling of cadmium and lead phytoextraction by Madagascar Periwinkle [Catharanthus roseus (L.) G.Don] in battery waste contaminated soil
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DOI: 10.1038/s41598-025-03080-x
Abstract: Remediation of heavy metal-contaminated soils is critical due to their persistent toxicity and threat to food security and ecosystem health. Therefore, a study was conducted during September to November 2024 to assess the phytoextraction potential… read more here.
Keywords: mechanistic kinetic; cadmium lead; phytoextraction; madagascar periwinkle ... See more keywords
Folivory elicits a strong defense reaction in Catharanthus roseus: metabolomic and transcriptomic analyses reveal distinct local and systemic responses
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40453
Abstract: Plants deploy distinct secondary metabolisms to cope with environment pressure and to face bio-aggressors notably through the production of biologically active alkaloids. This metabolism-type is particularly elaborated in Catharanthus roseus that synthesizes more than a… read more here.
Keywords: defense; elicits strong; catharanthus roseus; local systemic ... See more keywords
The specific responses to mechanical wound in leaves and roots of Catharanthus roseus seedlings by metabolomics
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Plant Interactions"
DOI: 10.1080/17429145.2018.1499970
Abstract: ABSTRACT The mechanical wound is one of the unavoidable threats to survival of plants. More researchers focus on the effect of mechanical wound to the over-ground tissues. And the effects of wound to roots were… read more here.
Keywords: wound leaves; tias pcs; catharanthus roseus; wound ... See more keywords