PU.1 and epigenetic signals modulate 1,25‐dihydroxyvitamin D3 and C/EBPα regulation of the human cathelicidin antimicrobial peptide gene in lung epithelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27702
Abstract: LL‐37, the only known human cathelicidin which is encoded by the human antimicrobial peptide (CAMP) gene, plays a critical role in protection against bacterial infection. We previously demonstrated that cathelicidin is induced by 1,25‐dihydroxyvitamin D3… read more here.
Keywords: cathelicidin; epithelial cells; camp; lung epithelial ... See more keywords
The relation of innate and adaptive immunity with viral-induced acute asthma attacks: Focusing on IP-10 and cathelicidin
Sign Up to like & getrecommendations! Published in 2017 at "Allergologia et Immunopathologia"
DOI: 10.1016/j.aller.2016.07.003
Abstract: Abstract Background Despite growing evidence suggesting potential association between innate and adaptive immunity in viral-induced acute asthma, there is paucity of data in this area. Objective This study aimed to investigate the association of innate… read more here.
Keywords: immunity; viral induced; asthma; cathelicidin ... See more keywords
Is cathelicidin a novel marker of diabetic microangiopathy in patients with type 1 diabetes?
Sign Up to like & getrecommendations! Published in 2017 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2017.09.023
Abstract: AIM The aim was to evaluate the relationship between higher serum cathelicidin levels with the occurrence of chronic microangiopathic complications in patients with diabetes mellitus type 1 (DM1). METHODS The study group consisted of 62… read more here.
Keywords: patients type; level; serum; type diabetes ... See more keywords
Antimicrobial and anti-inflammatory activities of short dodecapeptides derived from duck cathelicidin: Plausible mechanism of bactericidal action and endotoxin neutralization.
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DOI: 10.1016/j.ejmech.2020.112580
Abstract: Antimicrobial peptides (AMPs) have gained increasing attention to combat antibiotic-resistant pathogens. dCATH (duck cathelicidin) is a 20-residue avian cathelicidin with potent bactericidal activity. However, its therapeutic application is limited due to high mammalian cell cytotoxicity.… read more here.
Keywords: anti inflammatory; duck cathelicidin; dcath; cathelicidin ... See more keywords
Hypovitaminosis D and reduced cathelicidin are strongly correlated during the multidrug therapy against leprosy.
Sign Up to like & getrecommendations! Published in 2020 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2020.104373
Abstract: Mycobacterium leprae infection depends on the competence of the host immune defense to induce effective protection against this intracellular pathogen. The present study investigated the serum levels of vitamin D and the antimicrobial peptide cathelicidin,… read more here.
Keywords: hypovitaminosis reduced; reduced cathelicidin; multidrug therapy; strongly correlated ... See more keywords
Cathelicidin-NV from Nanorana ventripunctata effectively protects HaCaT cells, ameliorating ultraviolet B-induced skin photoaging
Sign Up to like & getrecommendations! Published in 2022 at "Peptides"
DOI: 10.1016/j.peptides.2021.170712
Abstract: Cathelicidins are diverse effector molecules in the vertebrate immune system and are related to immune regulation, inflammatory response, wound healing, and blood vessel formation. However, little is known about their free radical scavenging ability, especially… read more here.
Keywords: nanorana ventripunctata; cathelicidin; induced skin; skin photoaging ... See more keywords
Chronic kidney disease induces inflammation by increasing Toll–like receptor–4, cytokine and cathelicidin expression in neutrophils and monocytes
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DOI: 10.1016/j.yexcr.2018.02.022
Abstract: ABSTRACT TLR expression in neutrophils and monocytes is associated with increased cytokine synthesis, resulting in increased inflammation. However, the inflammatory pathway related to TLR and cathelicidin expression in these cells from CKD patients is unclear.… read more here.
Keywords: ckd patients; mcp; expression; expression neutrophils ... See more keywords
Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn’s disease, and clinical prognosis in inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2017 at "BMC Gastroenterology"
DOI: 10.1186/s12876-017-0619-4
Abstract: BackgroundCathelicidin (LL-37) is an antimicrobial peptide known to be associated with various autoimmune diseases. We attempt to determine if cathelicidin can accurately reflect IBD disease activity. We hypothesize that serum cathelicidin correlates with mucosal disease… read more here.
Keywords: disease; disease activity; stricture; mucosal disease ... See more keywords
Immunomodulatory effects of chicken cathelicidin-2 on a primary hepatic cell co-culture model
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DOI: 10.1371/journal.pone.0275847
Abstract: Cathelicidin-2 is an antimicrobial peptide (AMP) produced as part of the innate immune system of chickens and might be a new candidate to combat infection and inflammation within the gut-liver axis. Studying the hepatic immune… read more here.
Keywords: effects chicken; cell; cell culture; chicken cathelicidin ... See more keywords
Cathelicidin as a marker for subclinical cardiac changes and microvascular complications in children and adolescents with type 1 diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pediatric Endocrinology and Metabolism"
DOI: 10.1515/jpem-2022-0421
Abstract: Abstract Objectives To detect cathelicidin levels in pediatric patients with type 1 diabetes (T1D) as a potential marker for diabetic vascular complications and to assess its relation to diastolic dysfunction as an index for subclinical… read more here.
Keywords: cathelicidin levels; microvascular complications; marker; group patients ... See more keywords
Tissue-specific Regulation of Innate Immune Responses by Human Cathelicidin LL-37.
Sign Up to like & getrecommendations! Published in 2018 at "Current pharmaceutical design"
DOI: 10.2174/1381612824666180327113418
Abstract: Cathelicidins form one of the major families of antimicrobial peptides and have been identified in many vertebrates, including humans. LL-37, the only human member of the cathelicidin family, is detected in most sites of the… read more here.
Keywords: cathelicidin; innate immune; tissue specific; specific regulation ... See more keywords