Pro-cathepsin D, Prosaposin, and Progranulin: Lysosomal Networks in Parkinsonism.
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DOI: 10.1016/j.molmed.2020.07.004
Abstract: Mutations in GBA1, the gene encoding the lysosomal hydrolase glucocerebrosidase (GCase), are a risk factor for parkinsonism. Pursuing the potential mechanisms underlying this risk in aging neurons, we propose a new network uniting three major… read more here.
Keywords: pro cathepsin; prosaposin progranulin; cathepsin prosaposin; prosaposin ... See more keywords