Cationic oligonucleotide derivatives and conjugates: A favorable approach for enhanced DNA and RNA targeting oligonucleotides
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DOI: 10.3762/bjoc.17.125
Abstract: Antisense oligonucleotides (ASOs) have the ability of binding to endogenous nucleic acid targets, thereby inhibiting the gene expression. Although ASOs have great potential in the treatment of many diseases, the search for favorable toxicity profiles… read more here.
Keywords: derivatives conjugates; cationic oligonucleotide; amine groups; cationic amine ... See more keywords