LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "cationic antimicrobial" as a keyword



Photo by bermixstudio from unsplash

Cationic antimicrobial peptide and its poly-N-substituted glycine congener: Antibacterial and antibiofilm potential against A. baumannii.

Sign Up to like & get
recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.08.062

Abstract: Acinetobacter baumannii is one of the clinically important nosocomial pathogen that has become resistant to most of the conventional antimicrobials. Biofilms formed by A. baumannii are difficult to eradicate, thereby highlighting the need for new therapeutic… read more here.

Keywords: peptide; poly substituted; antimicrobial peptide; peptide poly ... See more keywords
Photo from wikipedia

Structural Organization of Brevilaterin Biosynthesis in Brevibacillus laterosporus S62-9: A Novel MbtH-Independent Cationic Antimicrobial Peptide Synthetase System.

Sign Up to like & get
recommendations! Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c01143

Abstract: Cationic antimicrobial peptides, produced by nonribosomal peptide synthetases (NRPSs), have received great attention in different applications, including as biocontrol and antimicrobial agents against foodborne pathogenic bacteria. Also, Brevibacillus spp. is a competent microorganism to produce… read more here.

Keywords: system; cationic antimicrobial; antimicrobial peptide; brevibacillus laterosporus ... See more keywords
Photo by matnapo from unsplash

Lysine Stapling Screening Provides Stable and Low Toxic Cationic Antimicrobial Peptides Combating Multidrug-Resistant Bacteria In Vitro and In Vivo.

Sign Up to like & get
recommendations! Published in 2021 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.1c01754

Abstract: Cationic antimicrobial peptides (CAMPs) are promising for treatment of multidrug-resistant (MDR) bacteria-caused infections. However, clinical application of CAMPs has been hampered mostly due to their poor proteolytic stability and hemolytic toxicity. Recently, lysine-stapled CAMPs developed… read more here.

Keywords: cationic antimicrobial; antimicrobial peptides; stapling screening; lysine stapling ... See more keywords
Photo by nate_dumlao from unsplash

Converting Teixobactin into a Cationic Antimicrobial Peptide (AMP).

Sign Up to like & get
recommendations! Published in 2017 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.7b00834

Abstract: Teixobactin is a head to side chain cyclodepsipeptide that contains two positive charges. One is found in the cycle, as a result of the presence of the guanidino-unusual amino acid L-allo-End, while the other is… read more here.

Keywords: teixobactin; teixobactin cationic; positive charges; antimicrobial peptide ... See more keywords
Photo by alexblock from unsplash

Discovery of Novel Antimicrobial Peptides from Varanus komodoensis (Komodo Dragon) by Large-Scale Analyses and De-Novo-Assisted Sequencing Using Electron-Transfer Dissociation Mass Spectrometry.

Sign Up to like & get
recommendations! Published in 2017 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.6b00857

Abstract: Komodo dragons are the largest living lizards and are the apex predators in their environs. They endure numerous strains of pathogenic bacteria in their saliva and recover from wounds inflicted by other dragons, reflecting the… read more here.

Keywords: discovery; komodo dragon; cationic antimicrobial; antimicrobial peptides ... See more keywords
Photo by benjaminjsuter from unsplash

Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans

Sign Up to like & get
recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0182926

Abstract: Dermaseptin-B2 (DRS-B2) is a multifunctional cationic antimicrobial peptide (CAP) isolated from frog skin secretion. We previously reported that DRS-B2 possesses anticancer and antiangiogenic activities in vitro and in vivo. In the present study, we evaluated… read more here.

Keywords: drs; multifunctional cationic; antimicrobial peptide; partial implication ... See more keywords
Photo by mybbor from unsplash

Structure of the Cyclic, Cationic Antimicrobial Peptide (KKWWKF) in Octanol Solution: in silico Approach

Sign Up to like & get
recommendations! Published in 2020 at "Indonesian Journal of Chemistry"

DOI: 10.22146/ijc.49190

Abstract: Understanding the mechanism of antimicrobial activity of cyclo-peptides helps to design new drugs based on these compounds. A common aspect of the mechanisms provided for the creation of antimicrobial activity of cyclo-peptides is their interaction… read more here.

Keywords: cyclic cationic; peptide kkwwkf; structure cyclic; structure ... See more keywords
Photo from wikipedia

Antimicrobial activity of cationic antimicrobial peptides against stationary phase bacteria

Sign Up to like & get
recommendations! Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2022.1029084

Abstract: Antimicrobial peptides (AMPs) are ancient antimicrobial weapons used by multicellular organisms as components of their innate immune defenses. Because of the antibiotic crisis, AMPs have also become candidates for developing new drugs. Here, we show… read more here.

Keywords: cationic antimicrobial; antimicrobial activity; non dividing; antimicrobial peptides ... See more keywords
Photo from wikipedia

Effects of Synthetic Short Cationic Antimicrobial Peptides on the Catalytic Activity of Myeloperoxidase, Reducing Its Oxidative Capacity

Sign Up to like & get
recommendations! Published in 2022 at "Antioxidants"

DOI: 10.3390/antiox11122419

Abstract: Cationic antimicrobial peptides (CAMPs) have gained attention as promising antimicrobial therapeutics causing lower or no bacterial resistance. Considerable achievements have been made in designing new CAMPs that are highly active as antimicrobials. However, there is… read more here.

Keywords: cationic antimicrobial; synthetic short; antimicrobial peptides; catalytic activity ... See more keywords
Photo by nci from unsplash

Effects of Medicinal Leech-Related Cationic Antimicrobial Peptides on Human Blood Cells and Plasma

Sign Up to like & get
recommendations! Published in 2022 at "Molecules"

DOI: 10.3390/molecules27185848

Abstract: Cationic antimicrobial peptides (CAMPs) are considered as next-generation antibiotics with a lower probability of developing bacterial resistance. In view of potential clinical use, studies on CAMP biocompatibility are important. This work aimed to evaluate the… read more here.

Keywords: cationic antimicrobial; antimicrobial peptides; medicinal leech; blood ... See more keywords
Photo by towfiqu999999 from unsplash

Selective Induction of Intrinsic Apoptosis in Retinoblastoma Cells by Novel Cationic Antimicrobial Dodecapeptides

Sign Up to like & get
recommendations! Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14112507

Abstract: Host defense peptides represent an important component of innate immunity. In this work, we report the anticancer properties of a panel of hyper-charged wholly cationic antimicrobial dodecapeptides (CAPs) containing multiple canonical forms of lysine and… read more here.

Keywords: intrinsic apoptosis; cationic antimicrobial; hc3 hc5; retinoblastoma ... See more keywords