Cationic nanoparticles enhance T cell tumor infiltration and antitumor immune responses to a melanoma vaccine
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DOI: 10.1126/sciadv.abk3150
Abstract: In clinical settings, cancer vaccines as monotherapies have displayed limited success compared to other cancer immunotherapeutic treatments. Nanoscale formulations have the ability to increase the efficacy of cancer vaccines by combatting the immunosuppressive nature of… read more here.
Keywords: nanoparticles enhance; cationic nanoparticles; tumor; enhance cell ... See more keywords
Pyrazole-Enriched Cationic Nanoparticles Induced Early- and Late-Stage Apoptosis in Neuroblastoma Cells at Sub-Micromolar Concentrations
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16030393
Abstract: Neuroblastoma (NB) is a severe form of tumor occurring mainly in young children and originating from nerve cells found in the abdomen or next to the spine. NB needs more effective and safer treatments, as… read more here.
Keywords: cb1h nps; cationic nanoparticles; late stage; stage ... See more keywords
In Vivo Antidepressant Effect of Passiflora edulis f. flavicarpa into Cationic Nanoparticles: Improving Bioactivity and Safety
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DOI: 10.3390/pharmaceutics12040383
Abstract: A variety of neuroactive flavonoids can be found in the species of the Passiflora genus; however, their difficulty in crossing the blood–brain barrier limits their in vivo neuropharmacological activity. In this study, cationic nanoparticles were… read more here.
Keywords: cationic nanoparticles; passiflora edulis; edulis flavicarpa;
Targeted Anticancer Agent with Original Mode of Action Prepared by Supramolecular Assembly of Antibody Oligonucleotide Conjugates and Cationic Nanoparticles
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DOI: 10.3390/pharmaceutics15061643
Abstract: Despite their clinical success, Antibody-Drug Conjugates (ADCs) are still limited to the delivery of a handful of cytotoxic small-molecule payloads. Adaptation of this successful format to the delivery of alternative types of cytotoxic payloads is… read more here.
Keywords: cationic nanoparticles; targeted anticancer; antibody oligonucleotide; oligonucleotide conjugates ... See more keywords