The in vivo toxicological profile of cationic solid lipid nanoparticles
Sign Up to like & getrecommendations! Published in 2019 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-019-00657-8
Abstract: Cationic solid lipid nanoparticles (cSLNs) are considered as one of the most effective lipid nanocarriers for delivery of low water-solubility compounds and genetic materials. As the excipients used in the cSLN production are generally regarded… read more here.
Keywords: toxicological profile; cationic solid; lipid nanoparticles; vivo toxicological ... See more keywords
Cationic Solid SMEDDS of Efavirenz for Improved Oral Delivery: Development by Central Composite Design, In Vitro and In Vivo Evaluation
Sign Up to like & getrecommendations! Published in 2023 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02495-3
Abstract: Efavirenz (EFV) is an anti-HIV drug with high dose and 40% oral bioavailability (BA). The aim was to improve the bioavailability by designing cationic solid SMEDDS. Solubility data, ternary phase diagrams, and central composite design… read more here.
Keywords: solid smedds; smedds; central composite; cationic solid ... See more keywords
Design, Physical Characterizations, and Biocompatibility of Cationic Solid Lipid Nanoparticles in HCT-116 and 16-HBE Cells: A Preliminary Study
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28041711
Abstract: In this study, pEGFP-LUC was used as a model plasmid and three distinct cationic lipids (dioleyloxy-propyl-trimethylammonium chloride [DOTMA], dioleoyl trimethylammonium propane [DOTAP], and cetylpyridinium chloride [CPC]) were tested along with PEG 5000, as a nonionic… read more here.
Keywords: solid lipid; hbe; hct 116; cationic solid ... See more keywords