Regulation of CATSPER1 expression by the testis-determining gene SRY
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0205744
Abstract: CATSPER1 gene encodes a pore-forming and pH-sensing subunit of the CatSper Ca2+- permeable channel, a protein in the flagellum essential for sperm hyperactivation. Previous studies have shown that the murine Catsper1 gene promoter is regulated… read more here.
Keywords: transcription; gene sry; catsper1; expression ... See more keywords
Acrosomal exocytosis is compromised in CATSPER1 KO mouse sperm.
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DOI: 10.1530/rep-24-0486
Abstract: In brief Catsper is an essential calcium channel for sperm capacitation; however, its role in acrosomal exocytosis has not been fully elucidated. This study shows that the lack of Catsper channels in mouse sperm alters… read more here.
Keywords: catsper1; ca2; mouse sperm; exocytosis ... See more keywords
Down Regulation of Catsper1 Expression by Calmodulin Inhibitor (Calmidazolium): Possible Implications for Fertility
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158070
Abstract: The CatSper channel localizes exclusively in the flagella of sperm cells. The Catsper1 protein, together with three pore units, is essential for the CatSper Channel formation, which produces flagellum hyperactivation and confers sperm fertility. Catsper1… read more here.
Keywords: inhibitor calmidazolium; fertility; catsper1; regulation catsper1 ... See more keywords