Causal effects of COVID‐19 on cancer risk: A Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28722
Abstract: In contemporary literature, little attention has been paid to the association between coronavirus disease‐2019 (COVID‐19) and cancer risk. We performed the Mendelian randomization (MR) to investigate the causal associations between the three types of COVID‐19… read more here.
Keywords: cancer risk; causal associations; cancer; value ... See more keywords
Assessing the causal associations of insomnia with depressive symptoms and subjective well-being: a bidirectional Mendelian randomization study.
Sign Up to like & getrecommendations! Published in 2021 at "Sleep medicine"
DOI: 10.1016/j.sleep.2021.08.025
Abstract: BACKGROUND The interactions and associations between insomnia, depressive symptoms, and subjective well-being are complex, thus it is hard to explore the effect and direction of causalities. This bidirectional Mendelian randomization (MR) study was to assess… read more here.
Keywords: subjective well; depressive symptoms; insomnia depressive; symptoms subjective ... See more keywords
Causal associations between risk factors and common diseases inferred from GWAS summary data
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DOI: 10.1038/s41467-017-02317-2
Abstract: Health risk factors such as body mass index (BMI) and serum cholesterol are associated with many common diseases. It often remains unclear whether the risk factors are cause or consequence of disease, or whether the… read more here.
Keywords: risk; factors common; common diseases; risk factors ... See more keywords
Potential therapeutic targets for sarcopenia identified by Mendelian randomisation
Sign Up to like & getrecommendations! Published in 2023 at "Age and Ageing"
DOI: 10.1093/ageing/afad024
Abstract: Abstract Background Identifying sarcopenia’s causally associated plasma proteins would provide potential therapeutic targets. Methods We screened out sarcopenia-related proteins with genome-wide association studies (GWAS) summary data and cis-protein loci genetic instruments. Summary data of sarcopenia… read more here.
Keywords: causal associations; targets sarcopenia; mendelian randomisation; potential therapeutic ... See more keywords
Causal associations of alcohol with ECG-derived cardiovascular phenotypes in chinese adults
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Preventive Cardiology"
DOI: 10.1093/eurjpc/zwad125.172
Abstract: Type of funding sources: None. Heavy alcohol consumption is associated with increased risk of stroke, but its role, especially moderate drinking, in other types of cardiovascular disease (CVD) remains inconclusive. Understanding how alcohol intake affects… read more here.
Keywords: associations alcohol; causal associations; derived cardiovascular; ecg derived ... See more keywords
Causal associations of anthropometric measurements with osteoarthritis: A Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0279198
Abstract: Objective We believe that there is a causal relationship between waist circumference and knee osteoarthritis. To confirm the hypothesis, we have conducted this study. Methods Genetic variants associated with the five anthropometric variables were obtained… read more here.
Keywords: causal associations; circumference; osteoarthritis; knee osteoarthritis ... See more keywords
Causal Associations Between Basal Metabolic Rate and COVID-19.
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes"
DOI: 10.2337/db22-0610
Abstract: Many COVID-19 risk factors, including obesity and diabetes, are associated with an abnormal basal metabolic rate (BMR). We aimed to evaluate whether BMR could impact the susceptibility to or severity of COVID-19. We performed genetic… read more here.
Keywords: basal metabolic; causal associations; bmr; metabolic rate ... See more keywords
Causal Associations Among Diseases and Imaging Findings in Radiology Reports
Sign Up to like & getrecommendations! Published in 2022 at "Studies in health technology and informatics"
DOI: 10.3233/shti220487
Abstract: This study explored the ability to identify causal relationships between diseases and imaging findings from their co-occurrences in radiology reports. A natural language processing (NLP) system with negative-expression filtering detected positive mentions of 16,912 disorders,… read more here.
Keywords: radiology; among diseases; diseases imaging; causal associations ... See more keywords
Causal Associations of Obesity With Achilles Tendinopathy: A Two-Sample Mendelian Randomization Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.902142
Abstract: Background Achilles tendinopathy (AT) is associated with severe pain and is the cause of dysfunction and disability that are associated with significant reduction in social and economic benefits. Several potential risk factors have been proposed… read more here.
Keywords: causal associations; mendelian randomization; risk factors; risk ... See more keywords
Two-Sample Mendelian Randomization Analysis Investigates Causal Associations Between Gut Microbial Genera and Inflammatory Bowel Disease, and Specificity Causal Associations in Ulcerative Colitis or Crohn’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.921546
Abstract: Background Intestinal dysbiosis is associated with inflammatory bowel disease (IBD). Ulcerative colitis (UC) and Crohn’s disease (CD), two subtypes of IBD, are characterized by unique microbial signatures, respectively. However, it is unclear whether UC or… read more here.
Keywords: causal associations; genera; disease; microbial genera ... See more keywords
Causal Associations of Circulating Lipids with Osteoarthritis: A Bidirectional Mendelian Randomization Study
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14071327
Abstract: Osteoarthritis (OA) imposes an increasing social burden due to global activity limitations, especially among the aged. Links between circulating lipids and OA have been reported; however, confounding data from observational studies have hindered causal conclusions.… read more here.
Keywords: causal associations; randomization; associations circulating; mendelian randomization ... See more keywords