Integrative Multi‐Omics Approach for Improving Causal Gene Identification
Sign Up to like & getrecommendations! Published in 2024 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22601
Abstract: Transcriptome‐wide association studies (TWAS) have been widely used to identify thousands of likely causal genes for diseases and complex traits using predicted expression models. However, most existing TWAS methods rely on gene expression alone and… read more here.
Keywords: causal gene; multi omics; identification; gene ... See more keywords
BnaC7.ROT3, the causal gene of cqSL-C7, mediates silique length by affecting cell elongation in Brassica napus.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of experimental botany"
DOI: 10.1093/jxb/erab407
Abstract: Siliques are a major carbohydrate source of energy for later seed development in rapeseed (Brassica napus). Thus, silique length (SL) has received great attention from breeders. We previously detected a novel quantitative trait locus cqSL-C7… read more here.
Keywords: rot3; causal gene; bnac7 rot3; silique length ... See more keywords
Integrative multi-omics framework for causal gene discovery in Long COVID
Sign Up to like & getrecommendations! Published in 2025 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1013725
Abstract: Long COVID, or Post-Acute Sequelae of SARS-CoV-2 infection (PASC), affects an estimated 10–20% of COVID-19 patients and presents persistent multisystemic symptoms. Although demographic and clinical factors, such as age, sex, and comorbidities, contribute to risk,… read more here.
Keywords: causal gene; multi omics; omics framework; integrative multi ... See more keywords