Is there a causal link between intracellular Na elevation and metabolic remodelling in cardiac hypertrophy?
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Society Transactions"
DOI: 10.1042/bst20170508
Abstract: Alterations in excitation–contraction coupling and elevated intracellular sodium (Nai) are hallmarks of pathological cardiac remodelling that underline contractile dysfunction. In addition, changes in cardiac metabolism are observed in cardiac hypertrophy and heart failure (HF) that… read more here.
Keywords: cardiac hypertrophy; link intracellular; causal link; hypertrophy ... See more keywords
No causal link between herpes zoster and ischemic stroke: evidence from Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2024 at "Neurological Research"
DOI: 10.1080/01616412.2024.2363098
Abstract: ABSTRACT Objective The association between herpes zoster (HZ) and stroke has been the subject of much previous research. Nevertheless, the connection remains ambiguous. A two-sample Mendelian randomisation study was conducted to explore the potential causal… read more here.
Keywords: link herpes; stroke; causal link; herpes zoster ... See more keywords
Exploring causal link of 25-hydroxyvitamin D with eating disorder risk via bidirectional Mendelian randomization
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DOI: 10.1097/md.0000000000043539
Abstract: Eating disorders (EDs) are severe psychiatric diseases characterized by disordered dietary behavior and malnutrition. Previous observational studies found an ambiguous correlation between low levels of serum 25-hydroxyvitamin D (25OHD) and EDs, and the causality remains… read more here.
Keywords: causal link; bidirectional mendelian; mendelian randomization; causal ... See more keywords
Inflammatory mediators: a causal link to hypertension during preeclampsia
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DOI: 10.1111/bph.14466
Abstract: Preeclampsia (PE) is a hypertensive disorder that occurs after 20 weeks of gestation, implicating the placenta as a key offender. PE is associated with an imbalance among B lymphocytes, CD4+ T lymphocytes, NK cells and… read more here.
Keywords: mediators causal; inflammatory mediators; link hypertension; causal link ... See more keywords
Causal link in iatrogenic crimes: problems of correlation of the categories of causality in forensic examination and Russian criminal law
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DOI: 10.25136/2409-7136.2020.10.34288
Abstract: The subject of this research is the Russian case law of conducting legal proceedings against the representatives of medical sphere based on the constituent elements of crime established by the Part 2 of the Article… read more here.
Keywords: examination; law; causal link; examination russian ... See more keywords
Causal link between hypothyroidism and gastric cancer risk: insights gained through multivariable Mendelian randomization and mediation analysis
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2024.1388608
Abstract: Background Gastric cancer (GC) is the third leading cause of cancer death worldwide, and hypothyroidism has been identified as a potential influencing factor. Despite known associations between hypothyroidism and various cancers, the causal link between… read more here.
Keywords: causal link; analysis; risk; gastric cancer ... See more keywords
Causal link between mental disorders and gastrointestinal diseases: a Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2025.1288619
Abstract: Background Observational research suggests that mental diseases may increase the risk of gastrointestinal diseases. However, the causal link between these conditions remains unclear. In this study, we conducted a two-sample Mendelian randomization (MR) analysis to… read more here.
Keywords: mental diseases; gastrointestinal diseases; mendelian randomization; causal link ... See more keywords
No evidence for a causal link between Helicobacter pylori infection and nonalcoholic fatty liver disease: A bidirectional Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1018322
Abstract: Although clinical studies have shown the possible relationship between Helicobacter pylori (H. pylori) infection and the development of nonalcoholic fatty liver disease (NAFLD), their causal relationship is still unknown. This bidirectional Mendelian randomization (MR) study… read more here.
Keywords: causal link; pylori infection; infection; study ... See more keywords